Secondary rituximab‐associated versus primary immunodeficiencies: The enigmatic border
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149667
Abstract: Rituximab (RTX), a chimeric monoclonal antibody targeting CD20‐positive cells, is a valuable treatment option for malignant and benign immune‐related disorders. The rationale of targeting the CD20 antigen relies on depletion of both healthy and autoreactive/malignant… read more here.
Keywords: cell; rtx; secondary rituximab; hypogammaglobulinemia ... See more keywords
Immunoglobulin serum levels in rituximab-treated patients with steroid-dependent nephrotic syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Nephrology"
DOI: 10.1007/s00467-019-04398-1
Abstract: Background Rituximab (RTX) is efficient in steroid-dependent nephrotic syndrome (SDNS) in pediatric and adult patients. The aim of this study is to describe hypogammaglobulinemia as a side effect of RTX treatment. Methods All pediatric patients… read more here.
Keywords: nephrology; age; steroid dependent; rtx ... See more keywords
Incidence and risk factors of rituximab-associated hypogammaglobulinemia in patients with complicated nephrotic syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Nephrology"
DOI: 10.1007/s00467-021-05304-4
Abstract: Hypogammaglobulinemia is a major adverse event after rituximab treatment; however, the precise incidence and risk factors are unclear in complicated steroid-dependent or frequently relapsing nephrotic syndrome (SDNS/FRNS) patients. This was a single-center, retrospective, observational study.… read more here.
Keywords: incidence; igg levels; risk factors; rituximab treatment ... See more keywords
A national survey of screening and management of hypogammaglobulinemia in Canadian transplantation centers
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DOI: 10.1111/tid.12706
Abstract: Infection remains one of the most common transplant‐related causes of death in patients undergoing transplantation. Secondary hypogammaglobulinemia (HGG) as a component of immune suppression and deficiency is associated with both solid organ transplantation (SOT) and… read more here.
Keywords: transplant; transplantation; survey screening; national survey ... See more keywords
Hypogammaglobulinemia Observed One Year after Rituximab Treatment for Idiopathic Thrombocytopenic Purpura
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DOI: 10.1155/2018/2096186
Abstract: We present the case of a 19-year-old female with severe hypogammaglobulinemia after having had treatment with rituximab for idiopathic thrombocytopenic purpura requiring intravenous immunoglobulins. She was admitted with the diagnosis of left-sided pneumonia with parapneumonic… read more here.
Keywords: treatment; year; one year; idiopathic thrombocytopenic ... See more keywords
Jejunal cavernous lymphangioma manifested as gastrointestinal bleeding with hypogammaglobulinemia in adult: A case report and literature review.
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DOI: 10.12998/wjcc.v8.i1.140
Abstract: BACKGROUND Lymphangioma is a benign lesion that rarely involves the gastrointestinal tract, especially in adults. Small bowel lymphangioma is a rare cause of gastrointestinal bleeding. Here, we report a case of an adult diagnosed with… read more here.
Keywords: gastrointestinal bleeding; cavernous lymphangioma; case; report ... See more keywords
Impact of Hypogammaglobulinemia on the Course of COVID-19 in a Non-Intensive Care Setting: A Single-Center Retrospective Cohort Study
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DOI: 10.3389/fimmu.2022.842643
Abstract: Background Severity and mortality of COVID-19 largely depends on the ability of the immune system to clear the virus. Among various comorbidities potentially impacting on this process, the weight and the consequences of an antibody… read more here.
Keywords: intensive care; covid; hypo; hypogammaglobulinemia ... See more keywords