Association between severe hypoglycaemia and risk of dementia in patients with type 2 diabetes mellitus: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3610
Abstract: The aim of this systematic review was to analyse whether there is an association between severe hypoglycaemia and the incidence of dementia in patients with type 2 diabetes mellitus. We systematically searched the MEDLINE, Scopus,… read more here.
Keywords: hypoglycaemia; risk; risk dementia; association severe ... See more keywords
Cognitive deficits associated with impaired awareness of hypoglycaemia in type 1 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4233-3
Abstract: Aims/hypothesisThe aim of this study was to compare cognitive function in adults with type 1 diabetes who have impaired awareness of hypoglycaemia with those who have normal awareness of hypoglycaemia. A putative association was sought… read more here.
Keywords: hypoglycaemia; impaired awareness; type diabetes; awareness hypoglycaemia ... See more keywords
Impact of flash glucose monitoring on hypoglycaemia in adults with type 1 diabetes managed with multiple daily injection therapy: a pre-specified subgroup analysis of the IMPACT randomised controlled trial
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4527-5
Abstract: Aims/hypothesisEvidence for the effectiveness of interstitial glucose monitoring in individuals with type 1 diabetes using multiple daily injection (MDI) therapy is limited. In this pre-specified subgroup analysis of the Novel Glucose-Sensing Technology and Hypoglycemia in… read more here.
Keywords: impact; group; hypoglycaemia; therapy ... See more keywords
A randomised controlled study of high intensity exercise as a dishabituating stimulus to improve hypoglycaemia awareness in people with type 1 diabetes: a proof-of-concept study
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-019-05076-5
Abstract: Aims/hypothesis Approximately 25% of people with type 1 diabetes have suppressed counterregulatory hormonal and symptomatic responses to insulin-induced hypoglycaemia, which renders them at increased risk of severe, disabling hypoglycaemia. This is called impaired awareness of… read more here.
Keywords: awareness; people type; study; hypoglycaemia ... See more keywords
Risk of hypoglycaemia with insulin degludec versus insulin glargine U300 in insulin-treated patients with type 2 diabetes: the randomised, head-to-head CONCLUDE trial
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-019-05080-9
Abstract: Aims/hypothesis A head-to-head randomised trial was conducted to evaluate hypoglycaemia safety with insulin degludec 200 U/ml (degludec U200) and insulin glargine 300 U/ml (glargine U300) in individuals with type 2 diabetes treated with basal insulin. Methods This… read more here.
Keywords: insulin; trial; hypoglycaemia; degludec ... See more keywords
Experimental non-severe hypoglycaemia substantially impairs cognitive function in type 2 diabetes: a randomised crossover trial
Sign Up to like & getrecommendations! Published in 2019 at "Diabetologia"
DOI: 10.1007/s00125-019-4964-4
Abstract: Aims/hypothesisPrevious studies have demonstrated a relationship between cognitive impairment and hypoglycaemia ( read more here.
Keywords: randomised crossover; non severe; hypoglycaemia; type diabetes ... See more keywords
Consequences of recurrent hypoglycaemia on brain function in diabetes
Sign Up to like & getrecommendations! Published in 2021 at "Diabetologia"
DOI: 10.1007/s00125-020-05369-0
Abstract: The discovery of insulin and its subsequent mass manufacture transformed the lives of people with type 1 and 2 diabetes. Insulin, however, was a drug with a ‘dark side’. It brought with it the risk… read more here.
Keywords: consequences recurrent; recurrent hypoglycaemia; hypoglycaemia brain; hypoglycaemia ... See more keywords
The suitability of patient-reported outcome measures used to assess the impact of hypoglycaemia on quality of life in people with diabetes: a systematic review using COSMIN methods
Sign Up to like & getrecommendations! Published in 2021 at "Diabetologia"
DOI: 10.1007/s00125-021-05382-x
Abstract: It is generally accepted that hypoglycaemia can negatively impact the quality of life (QoL) of people living with diabetes. However, the suitability of patient-reported outcome measures (PROMs) used to assess this impact is unclear. The… read more here.
Keywords: impact; validity; impact hypoglycaemia; hypoglycaemia ... See more keywords
Time below range alone is insufficient to identify severe hypoglycaemia risk in type 1 diabetes—the critical role of hypoglycaemia awareness: results from the SFDT1 study
Sign Up to like & getrecommendations! Published in 2025 at "Diabetologia"
DOI: 10.1007/s00125-025-06536-x
Abstract: Severe hypoglycaemia events (SHE) remain frequent in people with type 1 diabetes despite advanced diabetes technologies. We examined whether time below range (TBR) 3.9 mmol/l (70 mg/dl; TBR70) or 3.0 mmol/l (54 mg/dl; TBR54) is… read more here.
Keywords: iah; risk; type diabetes; hypoglycaemia ... See more keywords
Maternal obesity and degree of glucose intolerance on neonatal hypoglycaemia and birth weight: a retrospective observational cohort study in women with gestational diabetes mellitus
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-019-03554-x
Abstract: Gestational diabetes mellitus (GDM) is an increasing problem worldwide. Postnatal hypoglycaemia and excess foetal growth are known important metabolic complications of neonates born to women with diabetes. This retrospective cohort study aims to determine the… read more here.
Keywords: glucose intolerance; neonatal hypoglycaemia; maternal obesity; hypoglycaemia ... See more keywords
Cognitive Frailty in Older People with Type 2 Diabetes Mellitus: the Central Role of Hypoglycaemia and the Need for Prevention
Sign Up to like & getrecommendations! Published in 2019 at "Current Diabetes Reports"
DOI: 10.1007/s11892-019-1135-4
Abstract: Purpose of ReviewTo highlight the central role of hypoglycaemia in the causation of cognitive frailty and explore ways of recognition and prevention of hypoglycaemia.Recent FindingsCognitive frailty is an emerging new concept defined as the concomitant… read more here.
Keywords: older people; central role; cognitive frailty; hypoglycaemia ... See more keywords