Prevention and Management of Severe Hypoglycemia and Hypoglycemia Unawareness: Incorporating Sensor Technology
Sign Up to like & getrecommendations! Published in 2018 at "Current Diabetes Reports"
DOI: 10.1007/s11892-018-1065-6
Abstract: Purpose of ReviewIn addition to assisting in achieving improved glucose control, continuous glucose monitoring (CGM) sensor technology may also aid in detection and prevention of hypoglycemia. In this paper, we report on the current scientific… read more here.
Keywords: hypoglycemia; hypoglycemia unawareness; hypoglycemia hypoglycemia; technology ... See more keywords
A potential role for GPR107 in hypoglycemia unawareness
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731275
Abstract: Hypoglycemia unawareness (HU) is a major barrier to achieving glycemic control in diabetic patients and remains a severe complication for type 1 and many type 2 diabetics. Due to the limited availability of animal models… read more here.
Keywords: hypoglycemia unawareness; physiology; hypoglycemia; role gpr107 ... See more keywords
Hypoglycemia unawareness in type 1 diabetes suppresses brain responses to hypoglycemia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci97696
Abstract: BACKGROUND. Among nondiabetic individuals, mild glucose decrements alter brain activity in regions linked to reward, motivation, and executive control. Whether these effects differ in type 1 diabetes mellitus (T1DM) patients with and without hypoglycemia awareness… read more here.
Keywords: hypoglycemia; hypoglycemia unawareness; type diabetes; t1dm ... See more keywords
Hypoglycemia Unawareness in Insulinoma Revealed with Flash Glucose Monitoring Systems
Sign Up to like & getrecommendations! Published in 2018 at "Internal Medicine"
DOI: 10.2169/internalmedicine.1173-18
Abstract: The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed… read more here.
Keywords: unawareness insulinoma; hypoglycemia; hypoglycemia unawareness; flash glucose ... See more keywords
843-P: Hypoglycemia Unawareness Is Associated with Attachment and Reflective Functioning in People with Type 1 Diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes"
DOI: 10.2337/db19-843-p
Abstract: The importance of attachment has been studied extensively as a frame for understanding the self-care behaviours of people with diabetes and their relations with practitioners. A component of attachment is the ability to reflect upon… read more here.
Keywords: hypoglycemia; none; people type; reflective functioning ... See more keywords
The Anti-Narcolepsy Drug Modafinil Reverses Hypoglycemia Unawareness and Normalizes Glucose Sensing of Orexin Neurons in Male Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/db22-0639
Abstract: Perifornical hypothalamus (PFH) orexin glucose-inhibited (GI) neurons that facilitate arousal have been implicated in hypoglycemia awareness. Mice lacking orexin exhibit narcolepsy and orexin mediates the effect of the anti-narcolepsy drug, modafinil. Thus, hypoglycemia awareness may… read more here.
Keywords: pfh orexin; orexin; hypoglycemia unawareness; glucose sensitivity ... See more keywords