Possible Mechanisms of Axonal Transport Disturbances in Mouse Spinal Motoneurons Induced by Hypogravity.
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin of experimental biology and medicine"
DOI: 10.1007/s10517-020-05048-5
Abstract: The data obtained by transcriptome analysis of lumbar spinal cord segments, sciatic nerve, and the respiratory diaphragm of the mice performed after a space flight on board Bion-M1 biosatellite were processed by bioinformatic methods aimed… read more here.
Keywords: transport disturbances; possible mechanisms; motor; hypogravity ... See more keywords
Theoretical study on microgravity and hypogravity simulated by random positioning machine
Sign Up to like & getrecommendations! Published in 2020 at "Acta Astronautica"
DOI: 10.1016/j.actaastro.2020.07.047
Abstract: Abstract The random positioning machine (RPM), which continuously changes the gravity direction acting on a subject, can provide the simulated microgravity and planet hypogravity environments to the bioreactor on Earth. In this study, a theoretical… read more here.
Keywords: positioning machine; random positioning; rpm; hypogravity ... See more keywords
Effectiveness of exercise countermeasures for the prevention of musculoskeletal deconditioning in simulated hypogravity: A systematic review
Sign Up to like & getrecommendations! Published in 2021 at "Acta Astronautica"
DOI: 10.1016/j.actaastro.2021.05.005
Abstract: Abstract Background Exercise countermeasures are the main approach taken to protect astronauts from musculoskeletal deconditioning in microgravity (μg). Future exploration class missions will require astronauts to live on the surface of the Moon (0.16g) and… read more here.
Keywords: effectiveness exercise; review; exercise countermeasures; hypogravity ... See more keywords
An investigation of the single and combined effects of hypogravity and ionizing radiation on brain monoamine metabolism and rats' behavior.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences in space research"
DOI: 10.1016/j.lssr.2018.11.003
Abstract: BACKGROUND Ionizing radiation and hypogravity can cause central nervous system (CNS) dysfunctions. This is a key limiting factor for deep space missions. Up until now, the mechanisms through which they affect the neural tissue are… read more here.
Keywords: metabolism; ionizing radiation; monoamine; brain ... See more keywords
Muscle synergies inherent in simulated hypogravity running reveal flexible but not unconstrained locomotor control
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-023-50076-6
Abstract: With human space exploration back in the spotlight, recent studies have investigated the neuromuscular adjustments to simulated hypogravity running. They have examined the activity of individual muscles, whereas the central nervous system may rather activate… read more here.
Keywords: muscle synergies; simulated hypogravity; locomotor control; hypogravity running ... See more keywords
Hypogravity simulation using the Variable Gravity Suspension System: A technical report.
Sign Up to like & getrecommendations! Published in 2025 at "Experimental physiology"
DOI: 10.1113/ep092172
Abstract: Human movement has evolved within Earth's gravitational environment (1 g; -9.81 m s-2). Future human exploration of terrestrial bodies, including the Moon (0.17 g; -1.62 m s-2) and Mars (0.38 g; -3.71 m s-2), will require astronauts to live and work within reduced gravitational… read more here.
Keywords: system; gravity; technical report; hypogravity ... See more keywords
Human perception of whole body roll-tilt orientation in a hypogravity analog: underestimation and adaptation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of neurophysiology"
DOI: 10.1152/jn.00140.2018
Abstract: Overestimation of roll tilt in hypergravity ("G-excess" illusion) has been demonstrated, but corresponding sustained hypogravic conditions are impossible to create in ground laboratories. In this article we describe the first systematic experimental evidence that in… read more here.
Keywords: hypogravity analog; hypogravity; roll tilt; orientation ... See more keywords
An Empirical and Subjective Model of Upper Extremity Fatigue Under Hypogravity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.832214
Abstract: In the context of extra-terrestrial missions, the effects of hypogravity (0 < G < 1) on the human body can reduce the well-being of the crew, cause musculoskeletal problems and affect their ability to perform… read more here.
Keywords: mental workload; hypogravity; fatigue; endurance time ... See more keywords
A novel computational framework for the estimation of internal musculoskeletal loading and muscle adaptation in hypogravity
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2024.1329765
Abstract: Introduction: Spaceflight is associated with substantial and variable musculoskeletal (MSK) adaptations. Characterisation of muscle and joint loading profiles can provide key information to better align exercise prescription to astronaut MSK adaptations upon return-to-Earth. A case-study… read more here.
Keywords: reaction; muscle adaptation; muscle; msk ... See more keywords