Tau as a biomarker of cognitive impairment and neuropsychiatric symptom in Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.26043
Abstract: The A/T/N research framework has been proposed for the diagnosis and prognosis of Alzheimer's disease (AD). However, the spatial distribution of ATN biomarkers and their relationship with cognitive impairment and neuropsychiatric symptoms (NPS) need further… read more here.
Keywords: alzheimer disease; impairment; cognitive impairment; hypometabolism ... See more keywords
Hypermetabolism in the cerebellum and brainstem and cortical hypometabolism are independently associated with cognitive impairment in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-018-4085-1
Abstract: PurposeCognitive impairment (CI) in Parkinson’s disease (PD) is associated with a widespread reduction in cortical glucose metabolism and relative increases in the cerebellum and brainstem as measured using 18F-fluorodesoxyglucose (FDG) PET. We separately analysed CI-related… read more here.
Keywords: index; hypometabolism; hypermetabolism; disease ... See more keywords
Severe posterior hypometabolism but normal perfusion in a patient with chronic fatigue syndrome/myalgic encephalomyelitis revealed by PET/MRI
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-018-4229-3
Abstract: Chronic fatigue syndrome/myalgic encephalitis (CFS/ME) is a complex clinical condition defined by prolonged severe fatigue without medical or psychiatric causes, and by a subset of symptoms that mostly includes arthromyalgias, cognitive impairment, sleeping troubles, and… read more here.
Keywords: hypometabolism; syndrome myalgic; fatigue syndrome; chronic fatigue ... See more keywords
The predictive value of hypometabolism in focal epilepsy: a prospective study in surgical candidates
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04356-x
Abstract: PurposeFDG PET is an established tool in presurgical epilepsy evaluation, but it is most often used selectively in patients with discordant MRI and EEG results. Interpretation is complicated by the presence of remote or multiple… read more here.
Keywords: epilepsy; outcome; hypometabolism; focal epilepsy ... See more keywords
Reversible widespread brain 18F-FDG PET hypometabolism in chronic fatigue syndrome treated by hyperbaric oxygen therapy
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-05122-0
Abstract: An indication of 50 sessions of hyperbaric oxygen therapy (HBOT) over a period of 6 weeks was retained in a 31-yearold man presenting with a chronic fatigue syndrome (CFS) evolving for 15 months with asthenia,… read more here.
Keywords: oxygen; hypometabolism; fdg pet; fdg ... See more keywords
Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular neurobiology"
DOI: 10.1007/s12035-022-02793-8
Abstract: Cerebral glucose hypometabolism is a typical hallmark of Alzheimer's disease (AD), usually associated with ongoing neurodegeneration and neuronal dysfunction. However, underlying pathological processes are not fully understood and reproducibility in animal models is not well… read more here.
Keywords: study; tspo expression; tau deposition; hypometabolism ... See more keywords
Seizure-induced reduction in glucose utilization promotes brain hypometabolism during epileptogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2018.04.016
Abstract: Brain glucose hypometabolism is an early symptom of acquired epilepsy, its causative mechanism yet unclear. We suggest that a bidirectional positive feedback linking seizures and hypometabolism (hypometabolism induces seizures while seizures disrupt glucose metabolism) may… read more here.
Keywords: epileptogenesis; hypometabolism; seizure induced; glucose metabolism ... See more keywords
Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-28941-1
Abstract: Alzheimer's disease (AD) is defined by amyloid (A) and tau (T) pathologies, with T better correlated to neurodegeneration (N). However, T and N have complex regional relationships in part related to non-AD factors that influence… read more here.
Keywords: dissociation tau; neuronal hypometabolism; hypometabolism; pathology ... See more keywords
Severe Contralateral Striatal Hypometabolism in a Case of Diabetic Nonketotic Hyperglycemic Hemichorea on 18F-FDG PET/CT Brain.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Nuclear Medicine"
DOI: 10.1097/rlu.0000000000002844
Abstract: Chorea induced by diabetic nonketotic hyperglycemia is a rare and poorly understood entity with a favorable prognosis after correction of the hyperglycemia. We present a case of elderly diabetic woman with poorly controlled blood glucose… read more here.
Keywords: hypometabolism; fdg pet; diabetic nonketotic; nonketotic hyperglycemic ... See more keywords
Hypometabolism as the ultimate defence in stress response: how the comparative approach helps understanding of medically relevant questions
Sign Up to like & getrecommendations! Published in 2017 at "Acta Physiologica"
DOI: 10.1111/apha.12747
Abstract: First conceptualized from breath‐hold diving mammals, later recognized as the ultimate cell autonomous survival strategy in anoxia‐tolerant vertebrates and burrowing or hibernating rodents, hypometabolism is typically recruited by resilient organisms to withstand and recover from… read more here.
Keywords: defence stress; response; hypometabolism; stress ... See more keywords
Neural correlates of naming errors across different neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2020 at "Neurology"
DOI: 10.1212/wnl.0000000000010967
Abstract: Objective To investigate the types of errors produced in a picture naming task by patients with neurodegenerative dementia due to different etiologies and their neural correlates. Methods The same standardized picture naming test was administered… read more here.
Keywords: hypometabolism; correlates naming; neural correlates; naming errors ... See more keywords