Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's disease
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DOI: 10.1002/jnr.23777
Abstract: Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse pathological mechanisms including cerebral hypoperfusion and glucose hypometabolism. These risk factors trigger neuroinflammation and oxidative‐nitrosative stress… read more here.
Keywords: glucose hypometabolism; cerebral hypoperfusion; hypoperfusion glucose; hypoperfusion ... See more keywords
Perfusion-CT imaging in epileptic seizures
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DOI: 10.1007/s00415-018-9095-1
Abstract: IntroductionPCT is used in the diagnosis of acute neurological syndromes, particularly stroke. We aimed to evaluate PCT abnormalities in patients with acute epileptic seizures or status epilepticus (SE).MethodsWe collected patients undergoing acute PCT for the… read more here.
Keywords: post ictal; seizure; ais; hypoperfusion ... See more keywords
Effect of Methylene Blue and PI3K-Akt Pathway Inhibitors on the Neurovascular System after Chronic Cerebral Hypoperfusion in Rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-020-01572-1
Abstract: Methylene blue (MB) has a protective effect on cognitive decline caused by chronic hypoperfusion, but the specific mechanism is not clear. This article aims to determine whether MB protects vascular neurons through PI3K/Akt and plays… read more here.
Keywords: group; ly294002; effect; cch group ... See more keywords
[Influence of perfusion status on central and mixed venous oxygen saturation in septic patients].
Sign Up to like & getrecommendations! Published in 2017 at "Revista brasileira de anestesiologia"
DOI: 10.1016/j.bjan.2017.03.008
Abstract: BACKGROUND AND OBJECTIVES Although there is controversy regarding the role of venous oxygen saturation in the initial resuscitation of septic patients with hypoperfusion, these markers are still widely used. This study aimed to evaluate the… read more here.
Keywords: svco2; concordance; oxygen saturation; hypoperfusion ... See more keywords
Characteristics of a patient population of dementia with lewy bodies (DLB) and Parkinson’s disease with dementia (PDD) exhibiting frontal hypoperfusion in brain perfusion spect
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2017.08.2701
Abstract: 1. McKeith IG, et al. Neurology 2005;65:1863-72. 2. Emre M, et al. Mov Disord 2007;22:2314-24. 3. Takemoto M, et al. J Alzheimers Dis. 2016;52:205-11. 4. Kasuga K, et al. J Neurol Neurosurg Psychiatry. 2010;81:608-10. REFERENCES… read more here.
Keywords: dementia; patient population; hypoperfusion; characteristics patient ... See more keywords
Significance of N-isopropyl-[123I] p-iodoamphetamine single-photon emission computed tomography in detection of responsible hypoperfusion in hemichorea
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2019.07.072
Abstract: Hemichorea is relatively an uncommon clinical presentation while its known etiology are vascular, metabolic, neoplastic, infectious, autoimmune, and inherited disorders. In the acquired case of hemichorea, the most common cause is the cerebrovascular insult, which… read more here.
Keywords: isopropyl 123i; iodoamphetamine single; 123i iodoamphetamine; hypoperfusion ... See more keywords
Intermittent fasting attenuates inflammasome-associated apoptotic and pyroptotic death in the brain following chronic hypoperfusion
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2021.105109
Abstract: Chronic cerebral hypoperfusion (CCH) has been shown to initiate several inflammatory pathways that can contribute to cognitive deficits and memory loss in vascular cognitive impairment (VCI). Multi-protein complexes termed inflammasomes that may be involved in… read more here.
Keywords: death; apoptotic pyroptotic; intermittent fasting; hypoperfusion ... See more keywords
Which is responsible for aphasia by subcortical lesions? Subcortical lesions or the cortical hypoperfusion?
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DOI: 10.1080/01616412.2022.2112369
Abstract: ABSTRACT Cerebral lesions causing aphasia involve morphological and functional changes. In this study, it was aimed to explain the connection between aphasia and subcortical lesions with SPECT. The study included 30 patients diagnosed in the… read more here.
Keywords: aphasia subcortical; hypoperfusion; subcortical lesions; dominant hemisphere ... See more keywords
Reliability and Validity of Visual Estimation of Femoral Head Hypoperfusion on Perfusion MRI in Legg-Calve-Perthes Disease
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DOI: 10.1097/bpo.0000000000001945
Abstract: Supplemental Digital Content is available in the text. Background: Assessing the severity of Legg-Calve-Perthes disease is important for treatment decision-making and determining prognosis. Perfusion magnetic resonance imaging (MRI) scans have improved our ability to assess… read more here.
Keywords: hipvasc; femoral head; estimation; hypoperfusion ... See more keywords
Chronic hypoperfusion due to intracranial large artery stenosis is not associated with cerebral β-amyloid deposition and brain atrophy
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DOI: 10.1097/cm9.0000000000001918
Abstract: Abstract Background: Insufficient cerebral perfusion is suggested to play a role in the development of Alzheimer disease (AD). However, there is a lack of direct evidence indicating whether hypoperfusion causes or aggravates AD pathology. We… read more here.
Keywords: pathology; chronic hypoperfusion; hypoperfusion; brain atrophy ... See more keywords
Regional cerebral hypoperfusion after acute sleep deprivation
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DOI: 10.1097/md.0000000000014008
Abstract: Abstract Previous neuroimaging studies have shown that functional changes occur after acute sleep deprivation, which suggest detrimental effects of a lack of sleep on the intrinsic functional architecture of the brain. We aimed to identify… read more here.
Keywords: acute sleep; attention network; sleep deprivation; regional cerebral ... See more keywords