Articles with "hypoperfusion" as a keyword



Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's disease

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Published in 2017 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.23777

Abstract: Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse pathological mechanisms including cerebral hypoperfusion and glucose hypometabolism. These risk factors trigger neuroinflammation and oxidative‐nitrosative stress… read more here.

Keywords: glucose hypometabolism; cerebral hypoperfusion; hypoperfusion glucose; hypoperfusion ... See more keywords

Perfusion-CT imaging in epileptic seizures

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Published in 2018 at "Journal of Neurology"

DOI: 10.1007/s00415-018-9095-1

Abstract: IntroductionPCT is used in the diagnosis of acute neurological syndromes, particularly stroke. We aimed to evaluate PCT abnormalities in patients with acute epileptic seizures or status epilepticus (SE).MethodsWe collected patients undergoing acute PCT for the… read more here.

Keywords: post ictal; seizure; ais; hypoperfusion ... See more keywords

Real time organ hypoperfusion detection using Indocyanine Green in a piglet model

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Published in 2024 at "Surgical Endoscopy"

DOI: 10.1007/s00464-024-10938-0

Abstract: Preserving sufficient oxygen supply to the tissue is fundamental for maintaining organ function. However, our ability to identify those at risk and promptly recognize tissue hypoperfusion during abdominal surgery is limited. To address this problem,… read more here.

Keywords: hypoperfusion; organ hypoperfusion; perfusion monitoring; real time ... See more keywords

Efficacy of intravenous thrombolysis in patients with mild acute ischemic stroke and large vessel occlusion with different hypoperfusion volumes

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Published in 2025 at "Neurological Sciences"

DOI: 10.1007/s10072-025-08109-7

Abstract: To investigate early treatment strategies for patients with mild acute ischemic stroke and large vessel occlusion, we evaluated the efficacy of intravenous thrombolysis in patients with mild stroke and large vessel occlusion in different hypoperfusion… read more here.

Keywords: rate; vessel occlusion; large vessel; hypoperfusion ... See more keywords

Effect of Methylene Blue and PI3K-Akt Pathway Inhibitors on the Neurovascular System after Chronic Cerebral Hypoperfusion in Rats

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Published in 2020 at "Journal of Molecular Neuroscience"

DOI: 10.1007/s12031-020-01572-1

Abstract: Methylene blue (MB) has a protective effect on cognitive decline caused by chronic hypoperfusion, but the specific mechanism is not clear. This article aims to determine whether MB protects vascular neurons through PI3K/Akt and plays… read more here.

Keywords: group; ly294002; effect; cch group ... See more keywords

[Influence of perfusion status on central and mixed venous oxygen saturation in septic patients].

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Published in 2017 at "Revista brasileira de anestesiologia"

DOI: 10.1016/j.bjan.2017.03.008

Abstract: BACKGROUND AND OBJECTIVES Although there is controversy regarding the role of venous oxygen saturation in the initial resuscitation of septic patients with hypoperfusion, these markers are still widely used. This study aimed to evaluate the… read more here.

Keywords: svco2; concordance; oxygen saturation; hypoperfusion ... See more keywords

Characteristics of a patient population of dementia with lewy bodies (DLB) and Parkinson’s disease with dementia (PDD) exhibiting frontal hypoperfusion in brain perfusion spect

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Published in 2017 at "Journal of the Neurological Sciences"

DOI: 10.1016/j.jns.2017.08.2701

Abstract: 1. McKeith IG, et al. Neurology 2005;65:1863-72. 2. Emre M, et al. Mov Disord 2007;22:2314-24. 3. Takemoto M, et al. J Alzheimers Dis. 2016;52:205-11. 4. Kasuga K, et al. J Neurol Neurosurg Psychiatry. 2010;81:608-10. REFERENCES… read more here.

Keywords: dementia; patient population; hypoperfusion; characteristics patient ... See more keywords

Significance of N-isopropyl-[123I] p-iodoamphetamine single-photon emission computed tomography in detection of responsible hypoperfusion in hemichorea

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Published in 2019 at "Journal of Clinical Neuroscience"

DOI: 10.1016/j.jocn.2019.07.072

Abstract: Hemichorea is relatively an uncommon clinical presentation while its known etiology are vascular, metabolic, neoplastic, infectious, autoimmune, and inherited disorders. In the acquired case of hemichorea, the most common cause is the cerebrovascular insult, which… read more here.

Keywords: isopropyl 123i; iodoamphetamine single; 123i iodoamphetamine; hypoperfusion ... See more keywords
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Intermittent fasting attenuates inflammasome-associated apoptotic and pyroptotic death in the brain following chronic hypoperfusion

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Published in 2021 at "Neurochemistry International"

DOI: 10.1016/j.neuint.2021.105109

Abstract: Chronic cerebral hypoperfusion (CCH) has been shown to initiate several inflammatory pathways that can contribute to cognitive deficits and memory loss in vascular cognitive impairment (VCI). Multi-protein complexes termed inflammasomes that may be involved in… read more here.

Keywords: death; apoptotic pyroptotic; intermittent fasting; hypoperfusion ... See more keywords

Capillary regression leads to sustained local hypoperfusion by inducing constriction of upstream transitional vessels

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Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2321021121

Abstract: Significance Deterioration of the capillary network is a characteristic of many neurological diseases and can exacerbate neuronal dysfunction and degeneration due to poor blood perfusion. Here, we show that focal capillary injuries can induce vessel… read more here.

Keywords: hypoperfusion; capillary regression; upstream transitional; transitional vessels ... See more keywords

Which is responsible for aphasia by subcortical lesions? Subcortical lesions or the cortical hypoperfusion?

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Published in 2022 at "Neurological Research"

DOI: 10.1080/01616412.2022.2112369

Abstract: ABSTRACT Cerebral lesions causing aphasia involve morphological and functional changes. In this study, it was aimed to explain the connection between aphasia and subcortical lesions with SPECT. The study included 30 patients diagnosed in the… read more here.

Keywords: aphasia subcortical; hypoperfusion; subcortical lesions; dominant hemisphere ... See more keywords