Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02955-y
Abstract: Immune checkpoint inhibitors (ICIs) as a cancer immunotherapy have emerged as a treatment for multiple advanced cancer types. Because of enhanced immune responses, immune-related adverse events (irAEs), including endocrinopathies such as hypophysitis, have been associated… read more here.
Keywords: immune checkpoint; related hypophysitis; hypophysitis; ici related ... See more keywords
Transient hypophysitis in a patient treated by duvelisib for chronic lymphocytic leukemia
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DOI: 10.1007/s00277-017-2928-7
Abstract: Dear Editor, We report the case of a 67-year-old male patient, suffering from progressing chronic lymphocytic leukemia (CLL) and treated with the tyrosine kinase inhibitor (TKI) duvelisib for 6 months, who was admitted for severe… read more here.
Keywords: patient treated; lymphocytic leukemia; treated duvelisib; hypophysitis ... See more keywords
Intrachiasmatic abscess caused by IgG4-related hypophysitis
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-017-3288-8
Abstract: IntroductionAutoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.MethodsIn this study, we report a… read more here.
Keywords: abscess caused; caused igg4; intrachiasmatic abscess; hypophysitis ... See more keywords
Central diabetes insipidus (Infundibuloneuro hypophysitis): A late complication of COVID-19 infection
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-021-01627-z
Abstract: A novel coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has engulfed the world and has affected more than 151 million people, claiming more than 3.1 million lives across 192 countries… read more here.
Keywords: infection; hypophysitis; diabetes insipidus; central diabetes ... See more keywords
Cystic Lymphocytic Hypophysitis Mimicking Pituitary Apoplexy: Daunting Challenge.
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DOI: 10.1016/j.wneu.2018.06.230
Abstract: BACKGROUND Inflammatory lesions of the pituitary gland including hypophysitis are poorly understood, and it is difficult to make a correct diagnosis on the basis of only clinical and radiologic findings. CASE DESCRIPTION An otherwise healthy… read more here.
Keywords: lymphocytic hypophysitis; diagnosis; cystic lymphocytic; pituitary apoplexy ... See more keywords
Clinical Features, Magnetic Resonance Imaging, and Treatment Experience of 20 Patients with Lymphocytic Hypophysitis in a Single Center.
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DOI: 10.1016/j.wneu.2019.01.250
Abstract: OBJECTIVE Lymphocytic hypophysitis (LYH) is a rare autoimmune inflammatory disease of the pituitary gland. In this study, we aim to characterize LYH at presentation and focus on the management and prognosis of LYH. METHODS A… read more here.
Keywords: lymphocytic hypophysitis; clinical features; treatment; hypophysitis ... See more keywords
Clinical characteristics of rheumatic disease-associated hypophysitis: A case series and review of literature
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DOI: 10.1097/md.0000000000031338
Abstract: Rheumatic diseases have been reported to sometimes involve the pituitary gland. This study aims to characterize the clinical features and outcomes of patients with rheumatic disease-associated hypophysitis. We used the electronic medical record system in… read more here.
Keywords: hypophysitis; disease; rheumatic disease; associated hypophysitis ... See more keywords
Immune checkpoint inhibitor-induced hypophysitis: lessons learnt from a large cancer cohort
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Investigative Medicine"
DOI: 10.1136/jim-2021-002099
Abstract: Immune checkpoint inhibitors (ICIs) can cause pituitary dysfunction due to hypophysitis. We aimed to characterize ICI-induced hypophysitis and examine its association with overall survival in this single-center retrospective cohort study of adult patients with cancer… read more here.
Keywords: immune checkpoint; induced hypophysitis; cohort; hypophysitis ... See more keywords
Nivolumab induced hypophysitis in an advanced RCC patient
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DOI: 10.1177/10781552211072212
Abstract: Introduction Immune checkpoint inhibitors (ICIs) are being commonly used to treat solid tumours such as renal cell carcinoma. Hypophysitis is an acute or chronic inflammation of the pituitary gland and nivolumab or pembrolizumab induced hypophysitis… read more here.
Keywords: induced hypophysitis; patient; hypophysitis advanced; nivolumab induced ... See more keywords
A Case of Hypophysitis Following Immunization With the mRNA-1273 SARS-CoV-2 Vaccine
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Investigative Medicine High Impact Case Reports"
DOI: 10.1177/23247096211043386
Abstract: The emergence of a novel coronavirus and global pandemic raised the need for the rapid development of new vaccines to reduce the morbidity and mortality associated with Covid-19. Common side effects of these vaccines such… read more here.
Keywords: 1273 sars; immunization; hypophysitis; case ... See more keywords
Late-onset hypophysitis after discontinuation of nivolumab treatment for advanced skin melanoma: a case report
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DOI: 10.1186/s12902-021-00854-y
Abstract: Background Nivolumab is an anti-programmed cell death protein 1 antibody, typically used as cancer immunotherapy agent. Despite multiple clinical benefits it might cause autoimmune-related side-effects, often involving the endocrine system. To our knowledge, this is… read more here.
Keywords: treatment; discontinuation nivolumab; hypophysitis; case ... See more keywords