The role of Syk/IĸB‐α/NF‐ĸB pathway activation in the reversal effect of BAY 61‐3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan‐induced non‐septic shock
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DOI: 10.1111/1440-1681.12864
Abstract: Spleen tyrosine kinase (Syk), a non‐receptor tyrosine kinase, plays an important role in allergic diseases and inflammation. Syk triggers several intracellular signalling cascades including Toll‐like receptor signalling to activate inflammatory responses following fungal infection but… read more here.
Keywords: inflammation; syk; induced non; hypotension inflammation ... See more keywords