Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner
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DOI: 10.1002/glia.24237
Abstract: Hypothalamic astrocytes are particularly affected by energy‐dense food consumption. How the anatomical location of these glial cells and their spatial molecular distribution in the arcuate nucleus of the hypothalamus (ARC) determine the cellular response to… read more here.
Keywords: time; hfhs diet; triggers specific; hypothalamic astrocytes ... See more keywords
Age-Dependent Neurochemical Remodeling of Hypothalamic Astrocytes
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DOI: 10.1007/s12035-017-0786-x
Abstract: The hypothalamus is a crucial integrative center in the central nervous system, responsible for the regulation of homeostatic activities, including systemic energy balance. Increasing evidence has highlighted a critical role of astrocytes in orchestrating hypothalamic… read more here.
Keywords: age dependent; hypothalamic astrocytes; age; remodeling hypothalamic ... See more keywords
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain
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DOI: 10.3389/fnins.2020.589650
Abstract: The antipsychotic drug olanzapine is associated with serious obesity side effects. Hypothalamic astrocytes and associated toll-like receptor-4 (TLR4) signaling play an essential role in obesity pathogenesis. This study investigated the effect of olanzapine on astrocytes… read more here.
Keywords: hypothalamic astrocytes; olanzapine induced; tlr4 signaling; weight gain ... See more keywords