Hypothermic Machine Perfusion of Kidney Transplant: A Mini-Review.
Sign Up to like & getrecommendations! Published in 2021 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2021.09.011
Abstract: Most kidney grafts are marginal and from deceased donors, which yield worse clinical outcomes. Hypothermic machine perfusion has created a paradigm shift in kidney preservation. This mini-review summarizes the main points of hypothermic machine perfusion… read more here.
Keywords: hypothermic machine; machine; machine perfusion; perfusion kidney ... See more keywords
Hypothermic liver perfusion
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000000472
Abstract: Purpose of review The review describes recent developments in hypothermic machine liver perfusion with a special focus on underlying protective mechanisms, and the role of this perfusion technique in high-risk donor–recipient combinations. Recent findings To… read more here.
Keywords: hypothermic machine; liver perfusion; hypothermic liver; perfusion ... See more keywords
The Effects of Oxygenation on Ex Vivo Kidneys Undergoing Hypothermic Machine Perfusion
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation"
DOI: 10.1097/tp.0000000000002542
Abstract: Background Supplemental oxygenation of the standard hypothermic machine perfusion (HMP) circuit has the potential to invoke favorable changes in metabolism, optimizing cadaveric organs before transplantation. Methods Eight pairs of porcine kidneys underwent 18 hours of… read more here.
Keywords: perfusion; hypothermic machine; hmp air; machine perfusion ... See more keywords
Outcomes of donation after circulatory death kidneys undergoing hypothermic machine perfusion following static cold storage: A UK population‐based cohort study
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Transplantation"
DOI: 10.1111/ajt.14587
Abstract: Evidence is currently lacking regarding the outcomes of kidneys undergoing hypothermic machine perfusion (HMP) in patients in the United Kingdom. Using the National Health Service Blood and Transplant database, the authors compared outcomes for recipients… read more here.
Keywords: hypothermic machine; undergoing hypothermic; donation circulatory; kidneys undergoing ... See more keywords
Hypothermic Machine Perfusion Versus Static Cold Storage in Deceased Donor Kidney Transplantation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Sign Up to like & getrecommendations! Published in 2019 at "Artificial organs"
DOI: 10.1111/aor.13364
Abstract: Static cold storage (SCS) and hypothermic machine perfusion (HMP) are two primary options for renal allograft preservation. Compared with SCS, HMP decreased the incidence of delayed graft function (DGF) and protected graft function. However, more… read more here.
Keywords: hypothermic machine; machine perfusion; graft; kidney ... See more keywords
Optimizing porcine donor kidney preservation with normothermic or hypothermic machine perfusion: A systematic review.
Sign Up to like & getrecommendations! Published in 2021 at "Artificial organs"
DOI: 10.1111/aor.14039
Abstract: We present an updated overview of the literature comparing normothermic with hypothermic machine perfusion in porcine kidneys. We conducted a systematic literature review in Embase, Medline Epub (Ovid), Cochrane Central, Web of Science, and Google… read more here.
Keywords: hypothermic machine; perfusion; normothermic hypothermic; review ... See more keywords
Hypothermic machine perfusion is superior to static cold storage in deceased donor kidney transplantation: A meta‐analysis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Transplantation"
DOI: 10.1111/ctr.13814
Abstract: There remains a lack of consensus on the optimal storage method for deceased donor kidneys. This meta‐analysis compares storage with hypothermic machine perfusion (HMP) vs traditional static cold storage (SCS). read more here.
Keywords: hypothermic machine; storage; static cold; deceased donor ... See more keywords
Effects of SP600125 and hypothermic machine perfusion on livers donated after cardiac death in a pig allograft transplantation model
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Medical Research"
DOI: 10.1186/s40001-020-00472-9
Abstract: Background Hypothermic machine perfusion (HMP) improves the quality of donor livers for transplantation, both in animal models and in clinical practice. Treatment with SP600125, an inhibitor of c-Jun N-terminal kinase (JNK), can suppress the JNK… read more here.
Keywords: hypothermic machine; perfusion; hmp sp600125; sp600125 ... See more keywords
The Effect of Hypothermic Machine Perfusion to Ameliorate Ischemia-Reperfusion Injury in Donor Organs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.848352
Abstract: Hypothermic machine perfusion (HMP) has become the new gold standard in clinical donor kidney preservation and a promising novel strategy in higher risk donor livers in several countries. As shown by meta-analysis for the kidney,… read more here.
Keywords: hypothermic machine; reperfusion injury; machine perfusion; donor ... See more keywords
Trends and Outcomes of Hypothermic Machine Perfusion Preservation of Kidney Allografts in Simultaneous Liver and Kidney Transplantation in the United States
Sign Up to like & getrecommendations! Published in 2022 at "Transplant International"
DOI: 10.3389/ti.2022.10345
Abstract: Graphical Abstract Optimal kidney graft outcomes after simultaneous liver-kidney (SLK) transplant may be threatened by the increased cold ischemia time and hemodynamic perturbations of dual organ transplantation. Hypothermic machine perfusion (MP) of kidney allografts may… read more here.
Keywords: hypothermic machine; simultaneous liver; kidney; machine perfusion ... See more keywords
The Role of Endothelins, IL-18, and NGAL in Kidney Hypothermic Machine Perfusion
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9040417
Abstract: Ischemia-reperfusion injury (IRI) occurring after renal transplantation is a complex biochemical process that can be monitored by specific biomarkers. The roles of those are not yet fully elucidated. The aim of this study was to… read more here.
Keywords: hypothermic machine; machine perfusion; group; kidney ... See more keywords