Hypothermic oxygenated perfusion (HOPE) for fatty liver grafts in rats and humans.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2017.08.028
Abstract: BACKGROUND & AIMS Pretreatment of marginal organs by perfusion is a promising opportunity to make more organs available for transplantation. Protection of human donation after cardiac death (DCD) livers by a novel machine perfusion technique,… read more here.
Keywords: hypothermic oxygenated; liver grafts; hope; oxygenated perfusion ... See more keywords
Brief hypothermic oxygenated perfusion provides cardioprotection in a pig model of donation after circulatory death
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Cardio-Thoracic Surgery"
DOI: 10.1093/ejcts/ezaf061
Abstract: Abstract OBJECTIVES Donation after circulatory death provides excellent patient outcomes in heart transplantation; however, warm ischaemic graft damage remains a concern. We have reported that a brief period of hypothermic oxygenated perfusion prior to normothermic… read more here.
Keywords: hypothermic oxygenated; oxygenated perfusion; perfusion; model ... See more keywords
Cardiac Mitochondrial and Electrophysiological Changes in Transplanted Ovine Hearts Following Preservation by Hypothermic Oxygenated Perfusion
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DOI: 10.1097/tp.0000000000005490
Abstract: During heart transplantation (HTx), donor hearts are exposed to injury via brain death (BD) and cardiac preservation using static cold storage (SCS). Preservation using hypothermic oxygenated machine perfusion (HOPE) may reduce myocardial injury compared with… read more here.
Keywords: htx; hypothermic oxygenated; cardiac mitochondrial; donor ... See more keywords
Hypothermic Oxygenated Perfusion Preserves Myocardial Metabolism and Conduction in Heart Transplantation.
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DOI: 10.1097/tp.0000000000005560
Abstract: read more here.
Keywords: transplantation hypothermic; perfusion preserves; hypothermic oxygenated; oxygenated perfusion ... See more keywords
Outcome of liver transplantation with grafts from brain‐dead donors treated with dual hypothermic oxygenated machine perfusion, with particular reference to elderly donors
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Transplantation"
DOI: 10.1111/ajt.16996
Abstract: Prompted by the utilization of extended criteria donors, dual hypothermic oxygenated machine perfusion (D‐HOPE) was introduced in liver transplantation to improve preservation. When donors after neurological determination of death (DBD) are used, D‐HOPE effect on… read more here.
Keywords: hope; machine perfusion; dual hypothermic; oxygenated machine ... See more keywords
Hypothermic oxygenated perfusion in extended criteria donor liver transplantation—A randomized clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Transplantation"
DOI: 10.1111/ajt.17115
Abstract: Hypothermic Oxygenated Perfusion (HOPE) of the liver can reduce the incidence of early allograft dysfunction (EAD) and failure in extended criteria donors (ECD) grafts, although data from prospective studies are very limited. In this monocentric,… read more here.
Keywords: oxygenated perfusion; transplantation; graft; extended criteria ... See more keywords
Clinical assessment of liver metabolism during hypothermic oxygenated machine perfusion using microdialysis.
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DOI: 10.1111/aor.14066
Abstract: BACKGROUND While growing evidence supports use of hypothermic oxygenated machine perfusion (HOPE) in liver transplantation, its effects on liver metabolism are still incompletely understood. METHODS To assess liver metabolism during HOPE using microdialysis (MD), we… read more here.
Keywords: hypothermic oxygenated; liver metabolism; machine perfusion; hope ... See more keywords
Hypothermic Oxygenated Machine Perfusion (HOPE) During Total Vascular Exclusion With Veno‐Venous Bypass for Giant Hepatic Hemangioma Resection
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DOI: 10.1111/aor.15065
Abstract: Hypothermic oxygenated machine perfusion (HOPE) during total vascular exclusion with veno‐venous bypass for major hepatic resection is a safe procedure and could help to reduce ischemia–reperfusion lesions and related complications. read more here.
Keywords: hope total; machine perfusion; hypothermic oxygenated; oxygenated machine ... See more keywords
Ex-situ graft reduction (H67) during hypothermic oxygenated perfusion to prevent large-for-size syndrome in liver transplantation-A technical report.
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DOI: 10.1111/ctr.14995
Abstract: In this report, we discuss several technical and anatomical details of ex-situ H67 reduction of liver grafts during hypothermic oxygenated perfusion to prevent large-for-size syndrome in the case of anthropometric graft-recipient mismatch. read more here.
Keywords: oxygenated perfusion; prevent large; size syndrome; large size ... See more keywords
Hypothermic Oxygenated Perfusion Versus Static Cold Storage in Transplantation of Extended Criteria Liver Grafts: A Systematic Review and Meta‐Analysis
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DOI: 10.1111/ctr.70291
Abstract: The use of extended criteria donor livers (ECD) is becoming more routine in many transplant centers. These organs have higher risks for complications; however, hypothermic‐oxygenated perfusion (HOPE) was found to improve outcomes, including graft survival.… read more here.
Keywords: liver grafts; hypothermic oxygenated; oxygenated perfusion; extended criteria ... See more keywords