Hypothesis – buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission
Sign Up to like & getrecommendations! Published in 2017 at "Febs Letters"
DOI: 10.1002/1873-3468.12874
Abstract: Neural networks are optimized to detect temporal coincidence on the millisecond timescale. Here, we offer a synthetic hypothesis based on recent structural insights into SNAREs and the C2 domain proteins to explain how synaptic transmission… read more here.
Keywords: hypothesis buttressed; synaptic transmission; hypothesis; rings assemble ... See more keywords
Allelopathic effects of native and invasive Brassica nigra do not support the novel-weapons hypothesis.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of botany"
DOI: 10.1002/ajb2.1516
Abstract: PREMISE The novel-weapons hypothesis predicts that some plants are successful invaders because they release allelopathic compounds that are highly suppressive to naïve competitors in invaded ranges but are relatively ineffective against competitors in the native… read more here.
Keywords: hypothesis; brassica nigra; weapons hypothesis; novel weapons ... See more keywords
The Developmental Gene Hypothesis for Punctuated Equilibrium: Combined Roles of Developmental Regulatory Genes and Transposable Elements
Sign Up to like & getrecommendations! Published in 2020 at "BioEssays"
DOI: 10.1002/bies.201900173
Abstract: Theories of the genetics underlying punctuated equilibrium (PE) have been vague to date. Here the developmental gene hypothesis is proposed, which states that: 1) developmental regulatory (DevReg) genes are responsible for the orchestration of metazoan… read more here.
Keywords: developmental gene; gene hypothesis; developmental regulatory; hypothesis ... See more keywords
Is Alzheimer's disease an infectious neurological disease? A review of the literature
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2728
Abstract: Alzheimer's disease (AD) is a leading cause of dementia around the globe. Its pathogenesis is characterized primarily by the extracellular deposition of amyloid β peptides and intracellular neurofibrillary tangles. Despite the significant investments in neurological… read more here.
Keywords: disease; alzheimer disease; neurological disease; disease review ... See more keywords
Do microplastics impair male dominance interactions in fish? A test of the vector hypothesis
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.8620
Abstract: Abstract Microplastics (MPs) are widespread in aquatic environments and have become a critical environmental issue in recent years due to their adverse impacts on the physiology, reproduction, and survival of aquatic animals. Exposure to MPs… read more here.
Keywords: hypothesis; exposure mps; impair male; vector hypothesis ... See more keywords
Non‐visual cues and indirect strategies that enable discrimination of asymmetric mates
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.8790
Abstract: Abstract The postulates of developmental instability–sexual selection hypothesis is intensely debated among evolutionary biologists, wherein despite a large amount of empirical data, evidence for or against it has been largely inconclusive. A key assumption of… read more here.
Keywords: hypothesis; non visual; asymmetric mates; discrimination asymmetric ... See more keywords
Change in liana density over 30 years in a Bornean rain forest supports the escape hypothesis
Sign Up to like & getrecommendations! Published in 2021 at "Ecosphere"
DOI: 10.1002/ecs2.3537
Abstract: In two permanent plots of lowland dipterocarp forest at Danum a liana census in 1988 was repeated in 2018 using the same method. Trees ≥ 30 cm gbh (girth at breast height) were recorded for… read more here.
Keywords: escape; change liana; number; liana density ... See more keywords
Empirical support for the vascular apathy hypothesis: A structured review
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5217
Abstract: A systematic review of the relationship between subclinical small vessel disease (SSVD) in the general population and apathy to examine the hypothesis that apathy has a vascular basis. read more here.
Keywords: vascular apathy; empirical support; review; support vascular ... See more keywords
The role of the parahippocampal cortex in landmark‐based distance estimation based on the contextual hypothesis
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.26069
Abstract: Parahippocampal cortex (PHC) is a vital neural bases in spatial navigation. However, its functional role is still unclear. “Contextual hypothesis,” which assumes that the PHC participates in processing the spatial association between the landmark and… read more here.
Keywords: hypothesis; distance estimation; contextual hypothesis; distance ... See more keywords
No lanthanides‐based catalysis in eukaryotes
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.1982
Abstract: In the “Hypothesis” paper entitled “Lanthanides‐Based Catalysis in Eukaryotes” (IUBMB Life 2018 Nov;70(11):1067–1075), we analyzed the possibility that Ce3+‐dependent methanol dehydrogenases (MDHs) could be found not only in archaea and bacteria but also in eukaryotic… read more here.
Keywords: based catalysis; lanthanides based; catalysis eukaryotes; hypothesis ... See more keywords
Embedded ensemble encoding hypothesis: The role of the “Prepared” cell
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24240
Abstract: We here reconsider current theories of neural ensembles in the context of recent discoveries about neuronal dendritic physiology. The key physiological observation is that the dendritic plateau potential produces sustained depolarization of the cell body… read more here.
Keywords: state; embedded ensemble; plateau; ensemble encoding ... See more keywords