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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.789379
Abstract: Autoimmunity prevalence, as measured by antinuclear antibodies (ANA), is increasing in U.S. adolescents. Improved hygiene and cleaner environments in childhood may reduce exposure to infections and other immune challenges, resulting in improper immune responses to…
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Keywords:
hypothesis indicators;
prevalence antinuclear;
hygiene hypothesis;
indicators prevalence ... See more keywords