Domain wise differentiation of Mycobacterium tuberculosis H37 Rv hypothetical proteins: A roadmap to discover bacterial survival potentials.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2109
Abstract: Proteomic information revealed approximately 3923 proteins in Mycobacterium tuberculosis H37 Rv (M. tuberculosis) genome of which around ∼25% of proteins are hypothetical proteins (HPs). The present work comprises computational approaches to identify and characterize the… read more here.
Keywords: hypothetical proteins; tuberculosis; hps; tuberculosis h37 ... See more keywords
Targeting Essential Hypothetical Proteins of Pseudomonas aeruginosa PAO1 for Mining of Novel Therapeutics: An In Silico Approach
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DOI: 10.1155/2023/1787485
Abstract: As an omnipresent opportunistic bacterium, Pseudomonas aeruginosa PAO1 is responsible for acute and chronic infection in immunocompromised individuals. Currently, this bacterium is on WHO's red list where new antibiotics are urgently required for the treatment.… read more here.
Keywords: hypothetical proteins; pseudomonas aeruginosa; analysis; aeruginosa pao1 ... See more keywords
Comparative proteomic analysis to annotate the structural and functional association of the hypothetical proteins of S. maltophilia k279a and predict potential T and B cell targets for vaccination
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DOI: 10.1371/journal.pone.0252295
Abstract: Stenotrophomonas maltophilia is a multidrug-resistant bacterium with no precise clinical treatment. This bacterium can be a vital cause for death and different organ failures in immune-compromised, immune-competent, and long-time hospitalized patients. Extensive quorum sensing capability… read more here.
Keywords: analysis annotate; potential cell; hypothetical proteins; comparative proteomic ... See more keywords
Functional Annotation and Curation of Hypothetical Proteins Present in A Newly Emerged Serotype 1c of Shigella flexneri: Emphasis on Selecting Targets for Virulence and Vaccine Design Studies
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DOI: 10.3390/genes11030340
Abstract: Shigella flexneri is the principal cause of bacillary dysentery, contributing significantly to the global burden of diarrheal disease. The appearance and increase in the multi-drug resistance among Shigella strains, necessitates further genetic studies and development… read more here.
Keywords: proteins present; hypothetical proteins; emerged serotype; shigella flexneri ... See more keywords
Structural and Functional Annotation of Hypothetical Proteins from the Microsporidia Species Vittaforma corneae ATCC 50505 Using in silico Approaches
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DOI: 10.3390/ijms24043507
Abstract: Microsporidia are spore-forming eukaryotes that are related to fungi but have unique traits that set them apart. They have compact genomes as a result of evolutionary gene loss associated with their complete dependency on hosts… read more here.
Keywords: hypothetical proteins; hps; vittaforma corneae; annotation ... See more keywords