Neither Baseline nor Changes in Serum Triiodothyronine during Levothyroxine/Liothyronine Combination Therapy Predict a Positive Response to This Treatment Modality in Hypothyroid Patients with Persistent Symptoms
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DOI: 10.1159/000454878
Abstract: Background: Despite biochemical euthyroidism, some levothyroxine (L-T4)-treated hypothyroid patients report persisting symptoms and some of these patients are tentatively treated with a combination of L-T4 and liothyronine (L-T3). Combination therapy and the appropriate choice of… read more here.
Keywords: combination; hypothyroid patients; treatment; liothyronine combination ... See more keywords
Managing symptoms in hypothyroid patients on adequate levothyroxine: a narrative review
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DOI: 10.1530/ec-20-0205
Abstract: The current standard of care for hypothyroidism is levothyroxine (LT4) monotherapy to reduce levels of thyrotropin (thyroid-stimulating hormone, TSH) within its reference range and amelioration of any symptoms. A substantial minority continues to report hypothyroid-like… read more here.
Keywords: review; narrative review; managing symptoms; hypothyroid patients ... See more keywords
Haemostatic functions and metabolic profile of subclinical hypothyroid and hypothyroid patients.
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DOI: 10.3329/bjms.v17i4.38312
Abstract: Objectives: Both hypercoagulable and hypocoagulable states have been proposed for hypothyroidism, whether in overt or subclinical spectrum. The status of haemostatic functions, metabolic profile and their relationship in hypothyroid disorders need to be evaluated. Methods… read more here.
Keywords: functions metabolic; hypothyroid; subclinical hypothyroid; metabolic profile ... See more keywords
Risk of All-Cause Mortality in Levothyroxine-Treated Hypothyroid Patients: A Nationwide Korean Cohort Study
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DOI: 10.3389/fendo.2021.680647
Abstract: Background Although hypothyroidism is associated with various comorbidities, its relationship with increased all-cause mortality remains controversial. The aim of this nationwide retrospective cohort study was to investigate whether hypothyroid patients treated with levothyroxine had increased… read more here.
Keywords: hypothyroidism; risk; cause mortality; study ... See more keywords
Optimized Replacement T4 and T4+T3 Dosing in Male and Female Hypothyroid Patients With Different BMIs Using a Personalized Mechanistic Model of Thyroid Hormone Regulation Dynamics
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DOI: 10.3389/fendo.2022.888429
Abstract: Objective A personalized simulation tool, p-THYROSIM, was developed (1) to better optimize replacement LT4 and LT4+LT3 dosing for hypothyroid patients, based on individual hormone levels, BMIs, and gender; and (2) to better understand how gender… read more here.
Keywords: hormone; replacement; hypothyroid patients; male female ... See more keywords
DETECTION OF HYPOTHYROIDISM IN EARLY PREGNANCY: UNIVERSAL SCREENING
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DOI: 10.36106/ijar/1607490
Abstract: Background: Thyroid dysfunction is one of the most common endocrine disorders in women of childbearing (1), second only to diabetes mellitus.The aim of this systemic review was to determine whether an increased maternal TSH level… read more here.
Keywords: hypothyroidism; detection hypothyroidism; pregnancy; pregnant women ... See more keywords
Visual Evoked Potentials in Overt Hypothyroid Patients before and after Achievement of Euthyroidism
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DOI: 10.4103/ijem.ijem_366_16
Abstract: Background: Visual evoked potential (VEP) measures the time taken for visual stimulus to travel from the eye to the occipital cortex. Hypothyroidism affects the central nervous system (CNS) through its role in gene expression, myelin… read more here.
Keywords: treatment; visual evoked; hypothyroid patients; achievement euthyroidism ... See more keywords