Beneficial effects of Cinnamon on hepatic lipid metabolism are impaired in hypothyroid rats
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DOI: 10.1016/j.jff.2018.10.002
Abstract: Abstract Hypolipidemic effects of cinnamon (Cinnamomum zeylanicum) have been described in humans and in experimental animals. Hypothyroidism is frequently associated with hyperlipidemia. Here we investigated the effects of chronic ingestion of cinnamon on lipid metabolism… read more here.
Keywords: metabolism impaired; effects cinnamon; beneficial effects; hypothyroid rats ... See more keywords
Thymoquinone improved redox homeostasis in the heart and aorta of hypothyroid rats
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DOI: 10.1080/10641963.2022.2108046
Abstract: ABSTRACT Objectives Propylthiouracil (PTU) is a common drug that is used in medicine for treating hyperthyroidism. Furthermore, hypothyroidism can also be induced with PTU. Considering the antioxidant effects of thymoquinone (TMQ), this study was designed… read more here.
Keywords: hypothyroid rats; tmq; aorta tissues; heart ... See more keywords
Thymoquinone protects the testes of hypothyroid rats by suppressing pro-inflammatory cytokines and oxidative stress and promoting SIRT1 testicular expression
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DOI: 10.3389/fphar.2022.1040857
Abstract: Background: Hypothyroidism has been linked to many testicular structural and dysfunctional changes in males. Thymoquinone (TQ) has shown a potent testicular protective effect through its antioxidant, anti-inflammatory, antiapoptotic, fertility-enhancing, and endocrine modulatory activities. Objectives: This… read more here.
Keywords: hypothyroid rats; expression; inflammatory cytokines; pro inflammatory ... See more keywords
Inflammatory Immune Process and Depression-like Behavior in Hypothyroid Rats: A [18F] DPA-714 Micro Positron Emission Tomography Study
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DOI: 10.3390/ph16020279
Abstract: Hypothyroidism is closely related to mental disorders, mainly depression, through an as-yet-unknown mechanism. The cerebral inflammatory immune process has been implied to play a pivotal role in the onset of affective symptoms in several conditions.… read more here.
Keywords: behavior hypothyroid; hypothyroid rats; micro positron; test ... See more keywords