Indocyanine Green Aggregation-Induced Hypotonic Stress to Remodel Aloe Exosome-like Vesicles for Enhanced Tumor Penetration and Phototherapy.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.4c15440
Abstract: As ubiquitous transport nanovesicles in cell biology, plant exosome-like vesicles (PELVs) have enormous potential to deliver drugs safely and effectively. Drug encapsulation and mechanical stability of vesicles are key limitations influencing their delivery efficiency. However,… read more here.
Keywords: drug loading; exosome like; hypotonic stress; drug ... See more keywords
Calpain-mediated proteolysis of vimentin filaments is augmented in giant axonal neuropathy fibroblasts exposed to hypotonic stress
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.1101/2022.07.31.501244
Abstract: Giant Axonal Neuropathy (GAN) is a pediatric neurodegenerative disease caused by loss-of-function mutations in the E3 ubiquitin ligase adaptor gigaxonin, which is encoded by the GAN (KLHL16) gene. Gigaxonin regulates the degradation of multiple intermediate… read more here.
Keywords: stress; gan cells; vimentin; calpain ... See more keywords