Non-urate transporter 1, non-glucose transporter member 9-related renal hypouricemia and acute renal failure accompanied by hyperbilirubinemia after anaerobic exercise: a case report
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DOI: 10.1186/s12882-019-1618-1
Abstract: BackgroundRenal hypouricemia (RHUC) is an inherited heterogenous disorder caused by faulty urate reabsorption transporters in the renal proximal tubular cells. Anaerobic exercise may induce acute kidney injury in individuals with RHUC that is not caused… read more here.
Keywords: non; hypouricemia; injury; transporter ... See more keywords
A heterozygous variant in the SLC22A12 gene in a Sri Lanka family associated with mild renal hypouricemia
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DOI: 10.1186/s12887-018-1185-9
Abstract: BackgroundRenal hypouricemia is a rare heterogeneous inherited disorder characterized by impaired tubular uric acid transport, reabsorption insufficiency and /or acceleration of secretion. The affected individuals are predisposed to nephrolithiasis and recurrent episodes of exercise-induced acute… read more here.
Keywords: variant; hypouricemia; renal hypouricemia; gene ... See more keywords
Hypouricemia and Urate Transporters
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DOI: 10.3390/biomedicines10030652
Abstract: Hypouricemia is recognized as a rare disorder, defined as a serum uric acid level of 2.0 mg/dL or less. Hypouricemia is divided into an overexcretion type and an underproduction type. The former typical disease is… read more here.
Keywords: urate transporters; hypouricemia; hypouricemia urate;
Analysis of Purine Metabolism to Elucidate the Pathogenesis of Acute Kidney Injury in Renal Hypouricemia
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DOI: 10.3390/biomedicines10071584
Abstract: Renal hypouricemia is a disease caused by the dysfunction of renal urate transporters. This disease is known to cause exercise-induced acute kidney injury, but its mechanism has not yet been established. To analyze the mechanism… read more here.
Keywords: renal hypouricemia; acute kidney; kidney injury; hypouricemia ... See more keywords
Genetic Basis of the Epidemiological Features and Clinical Significance of Renal Hypouricemia
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DOI: 10.3390/biomedicines10071696
Abstract: A genetic defect in urate transporter 1 (URAT1) is the major cause of renal hypouricemia (RHUC). Although RHUC is detected using a serum uric acid (UA) concentration read more here.
Keywords: renal hypouricemia; epidemiological features; basis epidemiological; hypouricemia ... See more keywords