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Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14306
Abstract: Hypoxanthine‐guanine phosphoribosyltransferase (HGPRT) is a key enzyme in the purine salvage pathway. Here, the reverse reaction of HGPRT from the thermophilic bacterium Hungateiclostridium thermocellum was studied in the presence of IMP and pyrophosphate. As for the…
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Keywords:
phosphoribosyltransferase activated;
hypoxanthine guanine;
guanine phosphoribosyltransferase;
imp ... See more keywords
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Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.08.052
Abstract: Purine bases, synthesized de novo or recycled through the salvage pathway, are precursors of nucleotide synthesis and are essential in a variety of physiological processes including cell division, growth, signaling, energy metabolism and synthesis of…
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Keywords:
hgprt;
human homolog;
phosphoribosyl transferase;
guanine phosphoribosyl ... See more keywords
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Published in 2020 at "Immunobiology"
DOI: 10.1016/j.imbio.2020.151931
Abstract: INTRODUCTION The purpose of this study was to examine the effects of elevated Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) on the immune response in the tumor microenvironment. METHODOLOGY HPRT expression was evaluated in cancer patients and correlated…
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Keywords:
negatively correlated;
guanine phosphoribosyltransferase;
expression;
cell ... See more keywords