Hypoxanthine phosphoribosyltransferase (HPRT)‐deficiency is associated with impaired fertility in the female rat
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DOI: 10.1002/mrd.23413
Abstract: The purine hypoxanthine plays important role in regulating oocyte maturation and early embryonic development. The enzyme hypoxanthine phosphoribosyltransferase (HPRT) recycles hypoxanthine to generate substrates for nucleotide synthesis and key metabolites, and here we show that… read more here.
Keywords: phosphoribosyltransferase hprt; hypoxanthine phosphoribosyltransferase; hprt deficiency; hypoxanthine ... See more keywords