Near-Infrared Fluorescent Probes for Hypoxia Detection via Joint Regulated Enzymes: Design, Synthesis, and Application in Living Cells and Mice.
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DOI: 10.1021/acs.analchem.8b04249
Abstract: Hypoxia detection is emphasized with attention due to tumor and related diseases diagnosis, which could provide useful methods for exploring the mechanism of hypoxic tumor. Herein, we report two unprecedented hypoxia-sensitive probes that specifically switch-on… read more here.
Keywords: via joint; near infrared; hypoxia detection; regulated enzymes ... See more keywords