Hypoxia‐driven immunosuppression by Treg and type‐2 conventional dendritic cells in HCC
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32419
Abstract: Hypoxia is one of the central players in shaping the immune context of the tumor microenvironment (TME). However, the complex interplay between immune cell infiltrates within the hypoxic TME of HCC remains to be elucidated. read more here.
Keywords: conventional dendritic; treg type; hypoxia driven; driven immunosuppression ... See more keywords
Adrenal Medulla Chemo Sensitivity Does Not Compensate the Lack of Hypoxia Driven Carotid Body Chemo Reflex in Guinea Pigs.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-91137-3_21
Abstract: Guinea pigs (GP), originally from the Andes, have absence of hypoxia-driven carotid body (CB) reflex. Neonatal mammals have an immature CB chemo reflex and respond to hypoxia with metabolic changes arising from direct effects of… read more here.
Keywords: hypoxia driven; chemo reflex; hypoxia; carotid body ... See more keywords
Hypoxia driven glycation: Mechanisms and therapeutic opportunities.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.05.008
Abstract: Tumor masses are deprived of oxygen and characterized by enhanced glucose uptake followed by glycolysis. Elevated glucose levels induce non-enzymatic glycosylation or glycation of proteins which leads to accumulation of advanced glycation end products (AGE).… read more here.
Keywords: hypoxia driven; age; driven glycation; cancer ... See more keywords
Nanoparticle Delivery of MnO2 and Anti-angiogenic Therapy to Overcome Hypoxia-Driven Tumor Escape and Suppress Hepatocellular Carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c08473
Abstract: Anti-angiogenic therapy is widely administered in many cancers, and the anti-angiogenic drug sorafenib offers moderate benefits in advanced hepatocellular carcinoma (HCC). However, anti-angiogenic therapy can also lead to hypoxia-driven angiogenesis and immunosuppression in the tumor… read more here.
Keywords: hepatocellular carcinoma; hypoxia driven; angiogenic therapy; anti angiogenic ... See more keywords
Aryl Hydrocarbon Receptor Agonism Antagonizes the Hypoxia-driven Inflammation in Cystic Fibrosis.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0196oc
Abstract: Hypoxia contributes to the exaggerated yet ineffective airway inflammation that fails to oppose infections in cystic fibrosis (CF). However, the potential for impairment of essential immune functions by the hypoxia-inducible factor (HIF)-1α inhibition demands for… read more here.
Keywords: inflammation; driven inflammation; hypoxia driven; hypoxia ... See more keywords
Physical Fitness Differences, Amenable to Hypoxia-Driven and Sarcopenia Pathophysiology, between Sleep Apnea and COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19020669
Abstract: Handgrip strength is an indirect indicator of physical fitness that is used in medical rehabilitation for its potential prognostic value. An increasing number of studies indicate that COVID-19 survivors experience impaired physical fitness for months… read more here.
Keywords: hypoxia driven; physical fitness; strength; post covid ... See more keywords