A 17 gene panel for non‐small‐cell lung cancer prognosis identified through integrative epigenomic‐transcriptomic analyses of hypoxia‐induced epithelial–mesenchymal transition
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12491
Abstract: As a critical feature of the tumor microenvironment, hypoxia is known to be a potent inducer of tumor metastasis, and it has been proposed that the initial steps in metastasis involve epithelial–mesenchymal transition (EMT). The… read more here.
Keywords: mesenchymal transition; epithelial mesenchymal; non small; gene ... See more keywords
Protective effect of retinoic acid receptor α on hypoxia‐induced epithelial to mesenchymal transition of renal tubular epithelial cells associated with TGF‐β/MMP‐9 pathway
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biology International"
DOI: 10.1002/cbin.10982
Abstract: Retinoic acid receptor α (RARα), a member of family of the nuclear retinoic acid receptors (RARs), plays an essential role in various chronic kidney diseases (CKD). Renal tubular epithelial to mesenchymal transition (EMT) is a… read more here.
Keywords: tgf mmp; retinoic acid; renal tubular; tubular epithelial ... See more keywords
Investigations of hypoxia‐induced deoxyhemoglobin as a contrast agent for cerebral perfusion imaging
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.26131
Abstract: The assessment of resting perfusion measures (mean transit time, cerebral blood flow, and cerebral blood volume) with magnetic resonance imaging currently requires the presence of a susceptibility contrast agent such as gadolinium. Here, we present… read more here.
Keywords: hypoxia induced; gadolinium; induced deoxyhemoglobin; perfusion measures ... See more keywords
Deletion of long noncoding RNA EFNA3 aggravates hypoxia‐induced injury in PC‐12 cells by upregulation of miR‐101a
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27444
Abstract: Long noncoding RNAs (lncRNAs) have been reported to be involved in several neurological pathogenesis conditions including cerebral ischemia. In the current study, the functions of lncRNA EFNA3 on hypoxia‐injured rat adrenal pheochromocytoma (PC‐12) cells and… read more here.
Keywords: lncrna efna3; mir 101a; induced injury; hypoxia induced ... See more keywords
RELA promotes hypoxia‐induced angiogenesis in human umbilical vascular endothelial cells via LINC01693/miR‐302d/CXCL12 axis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28521
Abstract: Hypoxia‐induced angiogenesis plays a critical role in wound healing, which could be disturbed by multifactors. Upon hypoxia stimulation, CXCL12 and its receptor CXCR4 were significantly upregulated in human umbilical vascular endothelial cells (HUVECs); thus, we… read more here.
Keywords: mir 302d; cxcl12; angiogenesis; hypoxia induced ... See more keywords
Inhibition of lncRNA MEG3 protects renal tubular from hypoxia‐induced kidney injury in acute renal allografts by regulating miR‐181b/TNF‐α signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28553
Abstract: Early damage to transplanted organs initiates excess inflammation that deteriorates existing injury, which is a leading cause of graft loss. Long noncoding RNAs (lncRNAs) are recently thought to play a significant role in cellular homeostasis… read more here.
Keywords: tnf; tnf alpha; hypoxia induced; injury ... See more keywords
Protective effects of agrimonolide on hypoxia-induced H9c2 cell injury by maintaining mitochondrial homeostasis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30169
Abstract: Cardiomyocyte death caused by hypoxia is one of the main causes of myocardial infarction or heart failure, and mitochondria play an important role in this process. Agrimonolide (AM) is a monomeric component extracted from Agrimonia… read more here.
Keywords: h9c2 cells; induced h9c2; cell; hypoxia induced ... See more keywords
Hypoxia‐induced reprogrammed myoblasts enhance the formation of neuromuscular junctions: A pioneer study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30334
Abstract: We previously reported that muscle cells could reprogram into progenitors after traumatic injuries. These injury‐induced muscle stem cells (iMuSCs) have increased migration and differentiation capacities, including neuronal differentiation. Recent studies in our laboratory suggest that… read more here.
Keywords: hypoxia induced; muscle cells; formation neuromuscular; muscle ... See more keywords
Hypoxia‐induced tRNA‐derived fragments, novel regulatory factor for doxorubicin resistance in triple‐negative breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27533
Abstract: Triple‐negative breast cancer (TNBC) is an aggressive subtype of epithelial breast malignancy, and chemoresistance is the major obstacle for cancer therapy. TNBC is associated with a hypoxic phenotype, and hypoxia contributes to the chemoresistance in… read more here.
Keywords: hypoxia; tnbc; hypoxia induced; breast cancer ... See more keywords
miR‐20a inhibits hypoxia‐induced autophagy by targeting ATG5/FIP200 in colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23006
Abstract: Autophagy is a highly conserved lysosome‐mediated protective cellular process in which cytosolic components, including damaged organelles and long‐lived proteins, are cleared. Many studies have shown that autophagy was upregulated in hypoxic regions. However, the precise… read more here.
Keywords: mir 20a; atg5 fip200; cancer; induced autophagy ... See more keywords
Detection of Hypoxia-Induced and Iron Depletion-Induced Mitophagy in Mammalian Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/7651_2017_19
Abstract: Mitochondrial quality and quantity are not only regulated by mitochondrial fusion and fission but also by mitochondria degradation. Mitophagy, an autophagy specific for damaged or unnecessary mitochondria, is believed to be an important pathway for… read more here.
Keywords: hypoxia; iron depletion; detection hypoxia; hypoxia induced ... See more keywords