A hypoxia-activated NO donor for the treatment of myocardial hypoxia injury
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DOI: 10.1039/d2sc00048b
Abstract: As present NO donor drugs cannot localize to release NO at the hypoxic site, along with the short half-life and bidirectional regulation of NO, they are unable to overcome low bioavailability and side effects in… read more here.
Keywords: activated donor; myocardial hypoxia; hypoxia; hypoxia injury ... See more keywords
Role of circRNA circ_0000080 in myocardial hypoxia injury
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DOI: 10.1080/21655979.2022.2066752
Abstract: ABSTRACT This study aimed to investigate the potential role of circRNA circ_0000080 in myocardial hypoxia injury and the underlying mechanisms. Patients with myocardial hypoxia injury who were admitted to Xi’an No. 1 Hospital, China, were… read more here.
Keywords: circ 0000080; cox2; myocardial hypoxia; hypoxia injury ... See more keywords
Muscone improves hypoxia/reoxygenation (H/R)-induced neuronal injury by blocking HMGB1/TLR4/NF-κB pathway via modulating microRNA-142
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DOI: 10.7717/peerj.13523
Abstract: Previous reports have indicated that natural muscone has neuroprotective effects against cerebral hypoxia injury; however, little is known in regards to its pharmacological mechanism. In this study, we tried to evaluate the neuroprotective effects and… read more here.
Keywords: cell; hypoxia reoxygenation; muscone; hypoxia injury ... See more keywords