Hypoxia preconditioned plasma increases the expression of growth factors to accelerate diabetic wound healing by promoting angiogenesis
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-04665-2
Abstract: Hypoxia preconditioned plasma (HPP) is generated by cultivating blood under hypoxic conditions, allowing blood cells to naturally regulate the production of growth factors in response to hypoxia, which seems ideal for diabetic wound treatment. This… read more here.
Keywords: hpp; preconditioned plasma; diabetic wound; hypoxia preconditioned ... See more keywords
Hypoxia-Preconditioned Human Umbilical Cord Mesenchymal Stem Cells Transplantation Ameliorates Inflammation and Bone Regeneration in Peri-Implantitis Rat Model
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Dentistry"
DOI: 10.1055/s-0044-1791530
Abstract: Abstract Objective The failure of dental implant treatments is predominantly attributed to peri-implantitis, which entails chronic inflammation within the peri-implant tissue, ultimately leading to tissue degradation. Addressing this condition, human umbilical cord mesenchymal stem cell… read more here.
Keywords: inflammation; hypoxia preconditioned; peri implantitis; transplantation ... See more keywords
Hypoxia Preconditioned Serum (HPS) Promotes Osteoblast Proliferation, Migration and Matrix Deposition
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071631
Abstract: Interest in discovering new methods of employing natural growth factor preparations to promote bone fracture healing is becoming increasingly popular in the field of regenerative medicine. In this study, we were able to demonstrate the… read more here.
Keywords: preconditioned serum; hps; serum hps; hypoxia preconditioned ... See more keywords
In Vitro Comparison of Lymphangiogenic Potential of Hypoxia Preconditioned Serum (HPS) and Platelet-Rich Plasma (PRP)
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24031961
Abstract: Strategies for therapeutic lymphangiogenesis are gradually directed toward the use of growth factor preparations. In particular, blood-derived growth factor products, including Hypoxia Preconditioned Serum (HPS) and Platelet-rich Plasma (PRP), are both clinically employed for accelerating… read more here.
Keywords: hps platelet; preconditioned serum; prp; serum hps ... See more keywords
Comparison of the Effect of Different Conditioning Media on the Angiogenic Potential of Hypoxia Preconditioned Blood-Derived Secretomes: Towards Engineering Next-Generation Autologous Growth Factor Cocktails
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065485
Abstract: Hypoxia Preconditioned Plasma (HPP) and Serum (HPS) are regenerative blood-derived growth factor compositions that have been extensively examined for their angiogenic and lymphangiogenic activity towards wound healing and tissue repair. Optimization of these secretomes’ growth… read more here.
Keywords: growth; factor; blood derived; hypoxia preconditioned ... See more keywords
Hypoxia-Preconditioned Extracellular Vesicles from Mesenchymal Stem Cells Improve Cartilage Repair in Osteoarthritis
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DOI: 10.3390/membranes12020225
Abstract: In the past decade, mesenchymal stem cells (MSCs) have been widely used for the treatment of osteoarthritis (OA), and extracellular vesicles (EVs) may play a major role in the efficacy of this treatment. Hypoxia can… read more here.
Keywords: msc evs; cartilage repair; hypoxia preconditioned;
The Comparison of Normoxic and Hypoxic Mesenchymal Stem Cells in Regulating Platelet-derived Growth Factors and Collagen Serial Levels in Skin Excision Animal Models
Sign Up to like & getrecommendations! Published in 2023 at "Open Access Macedonian Journal of Medical Sciences"
DOI: 10.3889/oamjms.2023.10966
Abstract: BACKGROUND: The healing process of a skin excisions involves a complex cascade of cellular responses to reverse skin integrity formation. These processes require growth factors particularly platelet-derived growth factors (PDGF). On the other hand, hypoxia-… read more here.
Keywords: skin excision; hypoxia preconditioned; growth factors; preconditioned mscs ... See more keywords