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Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20221089
Abstract: Abstract Hypoxia and hypoxia-related genes regulate tumor initiation and progression. However, the exact roles that hypoxia plays in hepatocellular carcinoma (HCC) remain unclear. In the present study, we calculated the hypoxia score of each sample…
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Keywords:
hepatocellular carcinoma;
hypoxia;
hypoxia related;
model ... See more keywords
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Published in 2019 at "Histopathology"
DOI: 10.1111/his.13808
Abstract: The present study evaluates the impact of hypoxia‐related carbonic anhydrase IX and XII isoenzyme expression as a basic adaptive mechanism to neutralise intracellular acidosis in classical Hodgkin's lymphoma (cHL).
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Keywords:
carbonic anhydrase;
hodgkin lymphoma;
classical hodgkin;
related carbonic ... See more keywords
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Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/2974126
Abstract: Background Hypoxia was considered to be a prognostic indicator in a variety of solid tumors. This study aims at identifying the hypoxia-related genes (HRGs) in breast cancer (BC) and the feasibility of HRGs as a…
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Keywords:
independent prognostic;
based three;
breast cancer;
risk ... See more keywords
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Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/6373226
Abstract: Background Hypoxia is a typical microenvironmental feature of most solid tumors, affecting a variety of physiological processes. We developed a hypoxia-related prognostic risk score (HPRS) model to reveal tumor microenvironment (TME) and predict prognosis of…
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Keywords:
hypoxia related;
prognosis;
risk;
hprs model ... See more keywords
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Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/6419695
Abstract: Background Collagen type V alpha 1 chain (COL5A1) is a hypoxia-related gene (a collagen family protein) and participates in the formation of the extracellular matrix. Although some evidence supports a significant role for COL5A1 in…
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Keywords:
gene col5a1;
col5a1;
hypoxia related;
immune ... See more keywords
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Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/9935705
Abstract: The hypoxic tumor microenvironment and long noncoding RNAs (lncRNAs) are pivotal in cancer progression and correlate with the survival outcome of patients. However, the role of hypoxia-related lncRNAs (HRLs) in colorectal cancer (CRC) development remains…
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Keywords:
signature;
tumor microenvironment;
risk;
hypoxia related ... See more keywords
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Published in 2022 at "Journal of Biomaterials Applications"
DOI: 10.1177/08853282221125313
Abstract: Almost all eukaryotes need oxygen to maintain regular physiological activities. When the organism is under hypoxic situation for a persistent or periodic, it will induce irreversible physiological disorders and even pathological results. Hypoxia is closely…
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Keywords:
recent progress;
progress biocompatible;
fields recent;
related fields ... See more keywords
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Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0273524
Abstract: Hypoxia plays a major role in the etiology and pathogenesis of most of the leading causes of morbidity and mortality, whether cardiovascular diseases, cancer, respiratory diseases or stroke. Despite active research on hypoxia-signaling pathways, the…
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Keywords:
gene;
hypoxia;
hypoxia related;
novel hypoxia ... See more keywords
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Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0285096
Abstract: Introduction Placental dysfunction can lead to perinatal hypoxic events including stillbirth. Unless there is overt severe fetal growth restriction, placental dysfunction is frequently not identified in (near) term pregnancy, particularly because fetal size is not…
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Keywords:
gestation;
near term;
placental dysfunction;
hypoxia related ... See more keywords
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Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s344228
Abstract: Background Lung squamous cell carcinoma (LUSC) is a malignant tumour of the lung epithelium. A hypoxic environment can promote tumour cell proliferation and invasion. Therefore, this study aims to explore hypoxia-related genes and construct reliable…
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Keywords:
cellular processes;
immune microenvironment;
signature;
hypoxia related ... See more keywords
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Published in 2023 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s407759
Abstract: Purpose Myocardial infarction (MI) is a common cardiovascular disease, and its underlying pathological mechanism remains unclear. We aimed to develop a diagnostic model to distinguish different subtypes of MI. Patients and Methods The gene expression…
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Keywords:
diagnostic model;
myocardial infarction;
hypoxia related;
model ... See more keywords