miR‐192‐5p mediates hypoxia/reoxygenation‐induced apoptosis in H9c2 cardiomyocytes via targeting of FABP3
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.21873
Abstract: Myocardial ischemia/reperfusion (I/R) injury is a leading cause of morbidity and mortality. In this study, we investigated the role of miR‐192‐5p in hypoxia/reoxygenation (H/R)‐induced cardiomyocyte apoptosis. H9c2 cardiomyocytes were subjected to H/R and tested for… read more here.
Keywords: mir 192; apoptosis h9c2; hypoxia reoxygenation; apoptosis ... See more keywords
Propofol protects cardiomyocytes from hypoxia/reoxygenation injury via regulating MALAT1/miR‐206/ATG3 axis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22880
Abstract: Previous studies have shown that propofol (PPF) plays a protective role in ischemia–reperfusion (I/R) in multiple organs and tissues. This study was aimed to explore the mechanism of PPF in ameliorating myocardial ischemia‐reperfusion injury (MIRI).… read more here.
Keywords: hypoxia reoxygenation; atg3; malat1 mir; mir 206 ... See more keywords
Dexmedetomidine protects cardiomyocytes against hypoxia/reoxygenation injury via multiple mechanisms.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24119
Abstract: BACKGROUND Myocardial infarction (MI) is a serious cardiovascular disease associated with myocardial ischemia/reperfusion (I/R) injury. Dexmedetomidine (Dex), an α2-adrenoceptor agonist, has been reported to protect against I/R injury. We examined the cardioprotective effects of Dex… read more here.
Keywords: hypoxia reoxygenation; injury; measured using; dex ... See more keywords
Upregulation of FAM129B protects cardiomyocytes from hypoxia/reoxygenation‐induced injury by inhibiting apoptosis, oxidative stress, and inflammatory response via enhancing Nrf2/ARE activation
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23461
Abstract: Family with sequence similarity 129, member B (FAM129B) has been identified as a novel cytoprotective protein that facilitates the survival of detrimentally stimulated cells. However, whether FAM129B is involved in regulating cardiomyocyte survival after myocardial… read more here.
Keywords: fam129b; hypoxia reoxygenation; upregulation fam129b; injury ... See more keywords
Astragaloside IV protects human cardiomyocytes from hypoxia/reoxygenation injury by regulating miR-101a
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-020-03743-5
Abstract: Astragaloside IV (AS/IV) is one of the extracted components from the traditional Chinese medicine Astragalus which has been demonstrated to have potential capacity for anti-inflammation activity and for treating cardiovascular disease. Our purpose was to… read more here.
Keywords: hypoxia reoxygenation; human cardiomyocytes; injured cardiomyocytes; mir 101a ... See more keywords
FTO overexpression inhibits apoptosis of hypoxia/reoxygenation-treated myocardial cells by regulating m6A modification of Mhrt.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04069-6
Abstract: Heart failure (HF) is the end stage of many cardiovascular diseases and seriously threatens people's health. This article aimed to explore the biological role of fat-mass and obesity-associated gene (FTO) in HF. We constructed HF… read more here.
Keywords: treated myocardial; hypoxia reoxygenation; fto overexpression; myocardial cells ... See more keywords
Sevoflurane prevents hypoxia/reoxygenation-induced cardiomyocyte apoptosis by inhibiting PI3KC3-mediated autophagy
Sign Up to like & getrecommendations! Published in 2018 at "Human Cell"
DOI: 10.1007/s13577-018-00230-4
Abstract: Cardiomyocyte apoptosis plays an important role in ischemia/reperfusion (I/R)-induced myocardial injury. Autophagy is suggested to be widely implicated in regulating cell survival and death. The cardioprotection of sevoflurane postconditioning has been long recognized, but the… read more here.
Keywords: hypoxia reoxygenation; induced cardiomyocyte; sevoflurane; cardiomyocyte apoptosis ... See more keywords
The effects of dietary extract of mulberry leaf on growth performance, hypoxia-reoxygenation stress and biochemical parameters in various organs of fish
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DOI: 10.1016/j.aqrep.2020.100494
Abstract: Abstract The study explored the effects of extract of mulberry leaves (EML) on the growth performance and hypoxia-reoxygenation stress as well as biochemical parameters in various organs of crucian carp (Carassius auratus gibelio). The results… read more here.
Keywords: hypoxia reoxygenation; reoxygenation stress; crucian carp; growth ... See more keywords
PINK1 alleviates myocardial hypoxia-reoxygenation injury by ameliorating mitochondrial dysfunction.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.061
Abstract: PTEN inducible kinase-1 (PINK1) mutant induces mitochondrial dysfunction of cells, resulting in an inherited form of Parkinson's disease. However its exact role in the cardiomyocytes is unclear. The present study examined the function of PINK1… read more here.
Keywords: pink1; h9c2 cells; hypoxia reoxygenation; mitochondrial dysfunction ... See more keywords
The structure-activity relationship of ginsenosides on hypoxia-reoxygenation induced apoptosis of cardiomyocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.10.056
Abstract: Ginsenosides have been studied extensively in recent years due to their therapeutic effects in cardiovascular diseases. While most studies examined the different ginsenosides individually, few studies compare the therapeutic effects among the different types. This… read more here.
Keywords: hypoxia reoxygenation; reoxygenation induced; induced apoptosis; structure activity ... See more keywords
R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.126
Abstract: BACKGROUND & AIMS Leucine-rich repeat G-protein-coupled receptor 4 (LGR4) and its ligands R-spondin1-4 (Rspos) have been vastly investigated in embryonic development. The biological functions of Rspos-LGR4 system in liver remains largely unknown. Here, we explored… read more here.
Keywords: lgr4; hypoxia reoxygenation; protects hepatocytes; dmog induced ... See more keywords