Panax quinquefolium saponin Optimizes Energy Homeostasis by Modulating AMPK-Activated Metabolic Pathways in Hypoxia-Reperfusion Induced Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-020-3194-4
Abstract: To investigate the effects and underlying mechanisms of Panax quinquefolium saponin (PQS) on energy deficiency in hypoxia-reperfusion (H/R) induced cardiomyocytes. The H/R injury involved hypoxia for 3 h and then reperfusion for 2 h. Cardiomyocytes… read more here.
Keywords: pqs; hypoxia reperfusion; fat cd36; energy ... See more keywords
Visualizing and evaluating mitochondrial cysteine via near-infrared fluorescence imaging in cells, tissues and in vivo under hypoxia/reperfusion stress.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2021.126476
Abstract: Increasingly grim environmental pollutions are closely related with the occurrence and development of diseases. However, it's obscure how environmental stress disturbs the normal physiological process, and then how endogenous reactive species mend the cases. Hypoxia/reperfusion… read more here.
Keywords: hypoxia reperfusion; fluorescence; cys; cysteine ... See more keywords
MMP-9-mediated regulation of hypoxia-reperfusion injury-related neutrophil inflammation in an in vitro proximal tubular cell model
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DOI: 10.1080/0886022x.2021.1930558
Abstract: Abstract Background Hypoxia-reperfusion (HR) and inflammation are causes of renal allograft injury. Pathological evidence has indicated that ischemia followed by reperfusion leads to the proteolysis and destruction of the extracellular matrix (ECM) in renal tubular… read more here.
Keywords: mmp; hypoxia reperfusion; injury; group ... See more keywords
EGCG protects cardiomyocytes against hypoxia-reperfusion injury through inhibition of OMA1 activation
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DOI: 10.1242/jcs.220871
Abstract: ABSTRACT Mitochondria are important for energy production and cardiomyocyte homeostasis. OMA1, a metalloendopeptidase, initiates the proteolytic process of the fusion-allowing protein OPA1, to deteriorate mitochondrial structure and function. In this study, mouse embryonic fibroblasts (MEFs)… read more here.
Keywords: hypoxia reperfusion; cleavage; reperfusion; egcg ... See more keywords
miRNA transfection via poly(amidoamine)-based delivery vector prevents hypoxia/reperfusion-induced cardiomyocyte apoptosis.
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DOI: 10.2217/nnm-2019-0363
Abstract: Aim: Myocardial infarction is a tissue injury that leads to apoptosis of cardiomyocytes. This can be prevented by using miRNAs, but its delivery to cardiomyocytes is a major hurdle. We aimed to deliver miRNAs using… read more here.
Keywords: hypoxia reperfusion; apoptosis; delivery; reperfusion induced ... See more keywords
Cardiac Protection of a Novel Lupane-Type Triterpenoid from Injuries Induced by Hypoxia–Reperfusion
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169473
Abstract: Myocardial ischemia–reperfusion injury (MIRI) leads to cardiac remodeling and heart failure associated with acute myocardial infarction, which is one of the leading causes of death worldwide. Betulinic acid (BA), a widely distributed lupane-type triterpenoid, has… read more here.
Keywords: induced hypoxia; injuries induced; reperfusion; type triterpenoid ... See more keywords