Transcriptional activation of S100A2 expression by HIF‐1α via binding to the hypomethylated hypoxia response elements in HCC cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23393
Abstract: Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal cancers. Dysregulation of S100A2 has recently been found in many cancers including HCC. However, its regulatory mechanism in HCC remains poorly understood, especially in… read more here.
Keywords: s100a2; hypoxia response; response elements; hcc ... See more keywords
Involvement of the miR-462/731 cluster in hypoxia response in Megalobrama amblycephala
Sign Up to like & getrecommendations! Published in 2017 at "Fish Physiology and Biochemistry"
DOI: 10.1007/s10695-017-0341-8
Abstract: MicroRNAs (miRNAs) are non-coding small RNAs showing both evolutionarily conserved and unique features and are involved in nearly all biological processes. In the present study, the role played by miR-462/731 cluster miRNAs in hypoxia response… read more here.
Keywords: mir 462; 462 731; 731 cluster; hypoxia response ... See more keywords
ACBP4-WRKY70-RAP2.12 module positively regulates submergence-induced hypoxia response in Arabidopsis thaliana.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of integrative plant biology"
DOI: 10.1111/jipb.13647
Abstract: ACYL-CoA-BINDING PROTEINs (ACBPs) play crucial regulatory roles during plant response to hypoxia, but their molecular mechanisms remain poorly understood. Our study reveals that ACBP4 serves as a positive regulator of the plant hypoxia response by… read more here.
Keywords: hypoxia response; wrky70; submergence; response ... See more keywords
Spring viremia of carp virus infection induces hypoxia response in zebrafish by stabilizing hif1α
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Virology"
DOI: 10.1128/jvi.01491-24
Abstract: ABSTRACT The hypoxia signaling pathway controls hypoxia adaptation and tolerance of organisms, which is regulated by multiple mechanisms. Viral infection elicits various pathophysiological responses in the host. However, whether viral infection can affect the hypoxia… read more here.
Keywords: hypoxia signaling; hypoxia response; svcv infection; infection ... See more keywords
Identification of the effects of hypoxia on the liver tissues of Nile tilapia Oreochromis Niloticus
Sign Up to like & getrecommendations! Published in 2024 at "BMC Genomics"
DOI: 10.1186/s12864-024-10700-9
Abstract: Hypoxia stress resulted in mortality during the fish aquaculture program, affecting the sustainable development of the aquaculture industry. The Egyptian strain of O. niloticus showed a strong ability to hypoxia. In this study, a Nile… read more here.
Keywords: hypoxia response; metabolic pathways; niloticus; nile tilapia ... See more keywords
RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.
Sign Up to like & getrecommendations! Published in 2019 at "Wellcome Open Research"
DOI: 10.12688/wellcomeopenres.15044.1
Abstract: Background: Hypoxia-inducible factor (HIF) transcription factors are well known to control the transcriptional response to hypoxia. Given the importance of cellular response to hypoxia, a number of pharmacological agents to interfere with this pathway have… read more here.
Keywords: vhl; inhibitor; phd; response ... See more keywords
Integrative Analysis of Proteomics and Metabolism Reveals the Potential Roles of Arachidonic Acid Metabolism in Hypoxia Response in Mouse Spleen
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27228102
Abstract: High altitude hypoxia stress is the key cause of high-altitude pulmonary edema and spleen contraction. The molecular mechanism of immune response of various tissue systems to hypoxia stress remains lacking. In this study, we applied… read more here.
Keywords: metabolism; hypoxia response; acid metabolism; analysis ... See more keywords