Hypoxic-Inflammatory Responses under Acute Hypoxia: In Vitro Experiments and Prospective Observational Expedition Trial
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DOI: 10.3390/ijms21031034
Abstract: Induction of hypoxia-inducible-factor-1α (HIF-1α) pathway and HIF-target genes allow adaptation to hypoxia and are associated with reduced incidence of acute mountain sickness (AMS). Little is known about HIF-pathways in conjunction with inflammation or exercise stimuli… read more here.
Keywords: hypobaric hypoxia; hypoxia; hypoxic inflammatory; mrna expression ... See more keywords
Nobiletin Alleviates Astrocyte Activation and Oxidative Stress Induced by Hypoxia In Vitro
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DOI: 10.3390/molecules27061962
Abstract: Increasing evidence indicates that nobiletin (NOB) is a promising neuroprotective agent. Astrocyte activation plays a key role in neurodegenerative disorders. Thus, this study aims to investigate the effects of NOB on astrocyte activation and the… read more here.
Keywords: induced hypoxia; astrocyte activation; hypoxia vitro; oxidative stress ... See more keywords