Recombinant human growth hormone activates neuroprotective growth factors in hypoxic brain injury in neonatal mice.
Sign Up to like & getrecommendations! Published in 2021 at "Endocrinology"
DOI: 10.1210/endocr/bqab008
Abstract: Perinatal hypoxia severely disrupts cerebral metabolic and maturational programs beyond apoptotic cell death. Anti-apoptotic treatments such as erythropoietin are suggested to improve outcomes in hypoxic brain injury, however, the results are controversial. We analyzed neuroprotective… read more here.
Keywords: growth factors; growth hormone; brain; brain injury ... See more keywords
Further Evidence of Neuroprotective Effects of Recombinant Human Erythropoietin and Growth Hormone in Hypoxic Brain Injury in Neonatal Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158693
Abstract: Experimental in vivo data have recently shown complementary neuroprotective actions of rhEPO and growth hormone (rhGH) in a neonatal murine model of hypoxic brain injury. Here, we hypothesized that rhGH and rhEPO mediate stabilization of… read more here.
Keywords: brain; growth hormone; hypoxic brain; injury ... See more keywords
Bone marrow-derived mesenchymal stem cells ameliorate sodium nitrite-induced hypoxic brain injury in a rat model
Sign Up to like & getrecommendations! Published in 2017 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.221155
Abstract: Sodium nitrite (NaNO2) is an inorganic salt used broadly in chemical industry. NaNO2 is highly reactive with hemoglobin causing hypoxia. Mesenchymal stem cells (MSCs) are capable of differentiating into a variety of tissue specific cells… read more here.
Keywords: marrow derived; brain injury; brain; hypoxic brain ... See more keywords