Human adipose mesenchymal stromal cells growing into PCL‐nHA electrospun scaffolds undergo hypoxia adaptive ultrastructural changes
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DOI: 10.1002/biot.202200413
Abstract: Human Adipose‐Derived Mesenchymal Stem/Stromal Cells (hAD‐MSCs) have great potential for tissue regeneration. Since transplanted hAD‐MSCs are likely to be placed in a hypoxic environment, culturing the cells under hypoxic conditions might improve their post‐transplantation survival… read more here.
Keywords: hypoxic environment; nha nanofibers; human adipose; pcl nha ... See more keywords
The expression of Ldh-c in the skeletal muscle of plateau pika (Ochotona curzoniae) enhances adaptation to a hypoxic environment
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DOI: 10.1242/bio.024943
Abstract: ABSTRACT The plateau pika (Ochotona curzoniae) is a species of sprint-running alpine animals in the Qinghai-Tibet Plateau, which is a harsh highland hypoxic environment. Ldh-c is expressed in the testis, sperm and somatic tissues of… read more here.
Keywords: skeletal muscle; hypoxic environment; plateau pika; plateau ... See more keywords
Longitudinal Changes and Recovery in Heart Rate Variability of Young Healthy Subjects When Exposure to a Hypobaric Hypoxic Environment
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DOI: 10.3389/fphys.2021.688921
Abstract: Background: The autonomic nervous system (ANS) is crucial for acclimatization. Investigating the responses of acute exposure to a hypoxic environment may provide some knowledge of the cardiopulmonary system’s adjustment mechanism. Objective: The present study investigates… read more here.
Keywords: hypoxic environment; environment; heart; longitudinal changes ... See more keywords
Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric H3.3-Mutated Gliomas Recreate the Patient Tumor Complexity
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DOI: 10.3390/cancers11121875
Abstract: Background: Pediatric high-grade gliomas (pHGGs) are facing a very dismal prognosis and representative pre-clinical models are needed for new treatment strategies. Here, we examined the relevance of collecting functional, genomic, and metabolomics data to validate… read more here.
Keywords: tumor complexity; derived models; hypoxic environment; cell ... See more keywords