Effect of OSA on hypoxic and inflammatory markers during CPAP withdrawal: Further evidence from three randomized control trials
Sign Up to like & getrecommendations! Published in 2017 at "Respirology"
DOI: 10.1111/resp.12946
Abstract: Obstructive sleep apnoea (OSA) is associated with cardiovascular disease. Intermittent hypoxia, endothelial dysfunction and adipose tissue‐mediated inflammation have all been linked to cardiovascular disease in OSA. We therefore explored the effect of OSA on relevant… read more here.
Keywords: effect osa; markers cpap; osa hypoxic; effect ... See more keywords
NF-κB and TET2 promote macrophage reprogramming in hypoxia that overrides the immunosuppressive effects of the tumor microenvironment
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DOI: 10.1126/sciadv.adq5226
Abstract: Macrophages orchestrate tissue homeostasis and immunity. In the tumor microenvironment (TME), macrophage presence is largely associated with poor prognosis because of their reprogramming into immunosuppressive cells. We investigated the effects of hypoxia, a TME-associated feature,… read more here.
Keywords: promote macrophage; hypoxic inflammatory; tumor microenvironment; macrophage ... See more keywords
Hypoxic-Inflammatory Responses under Acute Hypoxia: In Vitro Experiments and Prospective Observational Expedition Trial
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DOI: 10.3390/ijms21031034
Abstract: Induction of hypoxia-inducible-factor-1α (HIF-1α) pathway and HIF-target genes allow adaptation to hypoxia and are associated with reduced incidence of acute mountain sickness (AMS). Little is known about HIF-pathways in conjunction with inflammation or exercise stimuli… read more here.
Keywords: hypobaric hypoxia; hypoxia; hypoxic inflammatory; mrna expression ... See more keywords