Broadband NIRS Cerebral Cytochrome-C-Oxidase Response to Anoxia Before and After Hypoxic-Ischaemic Injury in Piglets
Sign Up to like & getrecommendations! Published in 2018 at "Advances in Experimental Medicine and Biology"
DOI: 10.1007/978-3-319-91287-5_24
Abstract: Perinatal hypoxic ischaemic (HI) encephalopathy is associated with severe neurodevelopment problems and mortality. This study uses broadband continuous-wave near-infrared spectroscopy (NIRS) to assess the early changes in cerebral oxygenation and metabolism after HI injury in… read more here.
Keywords: cytochrome oxidase; hypoxic ischaemic; response anoxia; spectroscopy ... See more keywords
Nursing care in therapeutic hypothermia in neonates with hypoxic-ischaemic encephalopathy. Review of the literature.
Sign Up to like & getrecommendations! Published in 2020 at "Enfermeria intensiva"
DOI: 10.1016/j.enfi.2019.11.001
Abstract: INTRODUCTION Hypoxic-ischaemic encephalopathy is one of the main causes of neurological damage in the new-born. Therapeutic hypothermia is the current treatment to reduce mortality and disability in new-borns with this condition. OBJECTIVE To identify nursing… read more here.
Keywords: ischaemic encephalopathy; hypoxic ischaemic; hypothermia; therapeutic hypothermia ... See more keywords
Melatonin reduces hypoxic-ischaemic (HI) induced autophagy and apoptosis: An in vivo and in vitro investigation in experimental models of neonatal HI brain injury
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2016.11.050
Abstract: Melatonin has neuroprotective effects in many diseases, including neonatal hypoxic-ischaemic (HI) brain injury. The purpose of this study was to evaluate the neuroprotective effects of melatonin both in vivo and in vitro and associated molecular… read more here.
Keywords: vivo vitro; hypoxic ischaemic; melatonin; brain injury ... See more keywords
Altered biventricular function in neonatal hypoxic-ischaemic encephalopathy: a case-control echocardiographic study.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology in the young"
DOI: 10.1017/s1047951122002839
Abstract: BACKGROUND In newborns with hypoxic-ischaemic encephalopathy, more profound altered right and left ventricular function has been associated with mortality or brain injury. Mechanisms underlying cardiac dysfunction in this population are thought to be related to… read more here.
Keywords: hypoxic ischaemic; function; ventricle; ischaemic encephalopathy ... See more keywords
Therapeutic mechanism of cord blood mononuclear cells via the IL-8-mediated angiogenic pathway in neonatal hypoxic-ischaemic brain injury
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DOI: 10.1038/s41598-020-61441-0
Abstract: In a clinical trial of cerebral palsy, the level of plasma interleukin-8 (IL-8) was increased, correlated with motor improvement, after human umbilical cord blood mononuclear cell (hUCBC) infusion. This study aimed to elucidate the role… read more here.
Keywords: blood mononuclear; administration; hypoxic ischaemic; cord blood ... See more keywords
Functional reconstruction of the basal ganglia neural circuit by human striatal neurons in hypoxic–ischaemic injured brain
Sign Up to like & getrecommendations! Published in 2022 at "Brain"
DOI: 10.1093/brain/awac358
Abstract: Abstract Perinatal hypoxic–ischaemic encephalopathy is the leading cause of neonatal death and permanent neurological deficits, while the basal ganglia is one of the major nuclei that is selectively and greatly affected in the brains of… read more here.
Keywords: basal ganglia; hypoxic ischaemic; brain; ischaemic encephalopathy ... See more keywords
Abnormal expression and role of MicroRNA-214-3p/SLC8A1 in neonatal Hypoxic-Ischaemic encephalopathy.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of experimental pathology"
DOI: 10.1111/iep.12475
Abstract: Neonatal hypoxic-ischaemic encephalopathy (HIE) refers to brain damage caused by intra-uterine distress and asphyxia/hypoxia during the perinatal and neonatal periods. MicroRNA (MiR)-214-3p plays a critical role in cell growth and apoptosis. The aim of this… read more here.
Keywords: hypoxic ischaemic; role; expression; hie ... See more keywords
G487(P) Fact or fiction? brain herniation after hypoxic-ischaemic events in neonatal patients
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2017-313087.479
Abstract: Aims Conventional teaching in neonatology is that open cranial sutures protect newborns from brain herniation secondary to raised intracranial pressure. This case series aims to disseminate observations from a tertiary neonatal centre of brain herniation… read more here.
Keywords: hypoxic ischaemic; ischaemic events; pathology; brain herniation ... See more keywords
Disorders of vision in neonatal hypoxic-ischaemic encephalopathy: a systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2020-318998
Abstract: Objective Neonatal hypoxic-ischaemic encephalopathy (HIE) following perinatal asphyxia in term infants is associated with neonatal mortality and a high risk of neurodevelopmental impairment later in life. Visual disorders are an accepted complication of HIE and… read more here.
Keywords: ischaemic encephalopathy; hypoxic ischaemic; neonatal hypoxic; review ... See more keywords
Outcomes of neonatal hypoxic-ischaemic encephalopathy in centres with and without active therapeutic hypothermia: a nationwide propensity score-matched analysis
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DOI: 10.1136/archdischild-2020-320966
Abstract: Objective Therapeutic hypothermia (TH) for neonatal hypoxic-ischaemic encephalopathy (HIE), delivered mainly in tertiary cooling centres (CCs), reduces mortality and neurodisability. It is unknown if birth in a non-cooling centre (non-CC), without active TH, impacts short-term… read more here.
Keywords: propensity score; therapeutic hypothermia; ischaemic encephalopathy; neonatal hypoxic ... See more keywords
More than meets the eye: infant presenting with hypoxic ischaemic encephalopathy
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DOI: 10.1136/bcr-2017-223614
Abstract: We report a newborn infant who presented with poor Apgar scores and umbilical artery acidosis leading to the diagnosis of hypoxic ischaemic encephalopathy. During the course of the infant’s hospitalisation, subsequent workup revealed an underlying… read more here.
Keywords: ischaemic encephalopathy; hypoxic ischaemic; meets eye; eye infant ... See more keywords