Association of Hospital Resource Utilization With Neurodevelopmental Outcomes in Neonates With Hypoxic-Ischemic Encephalopathy
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.3770
Abstract: Key Points Question Is higher resource utilization, quantified by hospital costs, associated with survival without neurodevelopmental impairment among infants with hypoxic-ischemic encephalopathy treated with therapeutic hypothermia? Findings In this cohort study of 381 neonates with… read more here.
Keywords: neurodevelopmental outcomes; hypoxic ischemic; neonates hypoxic; resource utilization ... See more keywords
Melanin nanoparticles enhance the neuroprotection of mesenchymal stem cells against hypoxic-ischemic injury by inhibiting apoptosis and upregulating antioxidant defense.
Sign Up to like & getrecommendations! Published in 2022 at "Cell biology international"
DOI: 10.1002/cbin.11781
Abstract: Polydopamine nanoparticles are artificial melanin nanoparticles (MNPs) that show strong antioxidant activity. The effects of MNPs on the neuroprotection of mesenchymal stem cells (MSCs) against hypoxic-ischemic injury and the underlying mechanism have not yet been… read more here.
Keywords: mscs; neuroprotection; apoptosis; hypoxic ischemic ... See more keywords
Analysis of long noncoding RNA expression profiles in the whole blood of neonates with hypoxic‐ischemic encephalopathy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28138
Abstract: Long noncoding RNAs (lncRNAs) have been shown to participate in many biological processes. To investigate the expression profiles of lncRNAs and their potential functions in neonatal hypoxic‐ischemic encephalopathy (HIE), we detected the lncRNA and messenger… read more here.
Keywords: long noncoding; expression profiles; hypoxic ischemic; ischemic encephalopathy ... See more keywords
White matter injury in the neonatal hypoxic‐ischemic brain and potential therapies targeting microglia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24761
Abstract: Neonatal hypoxic–ischemic (H‐I) injury, which mainly causes neuronal damage and white matter injury (WMI), is among the predominant causes of infant morbidity (cerebral palsy, cognitive and persistent motor disabilities) and mortality. Disruptions to the oxygen… read more here.
Keywords: matter injury; hypoxic ischemic; brain; neonatal hypoxic ... See more keywords
Novel Contrast‐Enhanced Ultrasound Evaluation in Neonatal Hypoxic Ischemic Injury: Clinical Application and Future Directions
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Ultrasound in Medicine"
DOI: 10.1002/jum.14289
Abstract: Sensitive, specific, and safe bedside evaluation of brain perfusion is key to the early diagnosis, treatment, and improved survival of neonates with hypoxic ischemic injury. Contrast‐enhanced ultrasound (US) imaging is a novel imaging technique in… read more here.
Keywords: contrast enhanced; ischemic injury; hypoxic ischemic; enhanced ultrasound ... See more keywords
Diffusion pseudonormalization and clinical outcome in term neonates with hypoxic–ischemic encephalopathy
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Radiology"
DOI: 10.1007/s00247-018-4094-z
Abstract: BackgroundPseudonormalization of diffusion-weighted magnetic resonance imaging (MRI) can lead to underestimation of brain injury in newborns with hypoxic–ischemic encephalopathy (HIE), posing a significant problem. We have noticed that some neonates show pseudonormalization negativity on diffusion-weighted… read more here.
Keywords: diffusion; hypoxic ischemic; weighted imaging; diffusion weighted ... See more keywords
Intrapartum fetal monitoring and perinatal risk factors of neonatal hypoxic–ischemic encephalopathy
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05757-2
Abstract: Neonatal hypoxic–ischemic encephalopathy (HIE) in term infants, is a major cause of neonatal mortality and severe neurologic disability. To identify in labor fetal monitoring characteristic patterns and perinatal factors associated with neonatal HIE. Single-center retrospective… read more here.
Keywords: hypoxic ischemic; ischemic encephalopathy; monitoring; hie ... See more keywords
Neuroprotective effects of neurotropin in a mouse model of hypoxic–ischemic brain injury
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Anesthesia"
DOI: 10.1007/s00540-019-02655-z
Abstract: PurposeIschemic–hypoxic insult leads to detrimental effects on multiple organs. The brain is especially vulnerable, and it is hard to regenerate once damaged. Currently, therapeutic options are very limited. Previous studies have reported neuroprotective effects of… read more here.
Keywords: neuroprotective effects; hypoxic ischemic; ischemic brain; brain injury ... See more keywords
Photobiomodulation Therapy Attenuates Hypoxic-Ischemic Injury in a Neonatal Rat Model
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-018-1121-3
Abstract: Photobiomodulation (PBM) has been demonstrated as a neuroprotective strategy, but its effect on perinatal hypoxic-ischemic encephalopathy is still unknown. The current study was designed to shed light on the potential beneficial effect of PBM on… read more here.
Keywords: treatment; hypoxic ischemic; rat model; photobiomodulation ... See more keywords
Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling–Mediated Neuroinflammation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-021-01908-5
Abstract: Neonatal hypoxic-ischemic encephalopathy (HIE) is an obstinate disease that troubles neonatologists. At present, cognitive impairment after HIE has received increasing attention. Synaptic plasticity determines the development of cognitive function, so it is urgent to develop new… read more here.
Keywords: brain injury; synaptic plasticity; ischemic brain; resveratrol ... See more keywords
δ-Opioid Receptor-Nrf-2-Mediated Inhibition of Inflammatory Cytokines in Neonatal Hypoxic-Ischemic Encephalopathy
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1452-7
Abstract: Neonatal hypoxic-ischemic encephalopathy (HIE) causes serious neurological disability; there are, however, currently few promising therapies for it. We have recently shown that δ-opioid receptor (DOR) is neuroprotective by downregulating TNF-α. Since hypoxia-ischemia (HI) triggers a… read more here.
Keywords: opioid receptor; hypoxic ischemic; dor; inflammatory ... See more keywords