Hexagonally packed microwell plates for hypoxic microenvironment induction in tumorspheres
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Industrial and Engineering Chemistry"
DOI: 10.1016/j.jiec.2018.12.010
Abstract: Abstract The growth of a solid tumor in a confined microenvironment leads to increased compression, hypoxic/nutrition gradient within the tumor. However, Tumorspheres (TSs) cultured in free of spatial confinement do not exhibit physiological compressive stress.… read more here.
Keywords: plates hypoxic; hexagonally packed; microwell plates; hypoxic microenvironment ... See more keywords
Abstract B069: Spatial and single-cell proteomic landscaping of the hypoxic microenvironment in glioblastoma
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.liqbiop24-b069
Abstract: Glioblastoma (GBM) is a fatal adult solid tumour with median overall survival of 18-20 months post-diagnosis; contributing factors to therapeutic inefficacy include acquisition of genomic alterations post-therapy, immune evasion, deregulated hypervascularization, and tumor microenvironmental factors… read more here.
Keywords: hypoxic microenvironment; single cell; spatial single; cell proteomic ... See more keywords
The role of hypoxic microenvironment in autoimmune diseases
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1435306
Abstract: The hypoxic microenvironment, characterized by significantly reduced oxygen levels within tissues, has emerged as a critical factor in the pathogenesis and progression of various autoimmune diseases (AIDs). Central to this process is the hypoxia-inducible factor-1… read more here.
Keywords: microenvironment; role hypoxic; hypoxic microenvironment; autoimmune diseases ... See more keywords
Construction of Bone Hypoxic Microenvironment Based on Bone-on-a-Chip Platforms
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24086999
Abstract: The normal physiological activities and functions of bone cells cannot be separated from the balance of the oxygenation level, and the physiological activities of bone cells are different under different oxygenation levels. At present, in… read more here.
Keywords: bone; construction; hypoxic microenvironment; oxygen ... See more keywords
FNDC3B promotes epithelial-mesenchymal transition in tongue squamous cell carcinoma cells in a hypoxic microenvironment.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology reports"
DOI: 10.3892/or.2018.6231
Abstract: The primary reasons for the treatment failure of patients with oral tongue squamous cell carcinoma (OTSCC) are metastasis and tumor recurrence. Identifying the exact mechanisms underlying metastasis is a key point in improving patient prognosis.… read more here.
Keywords: tongue squamous; cell carcinoma; squamous cell; metastasis ... See more keywords