Protective Effects from the Ischemic/Hypoxic Stress Induced by Labor in the High-Altitude Tibetan Placenta
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00443-9
Abstract: Labor and vaginal delivery cause acute ischemic/hypoxic insult to the placenta. Previous studies demonstrate that placentas from high altitude non-natives showed blunted responses to ischemic/hypoxic insult caused by labor and vaginal birth, and there were… read more here.
Keywords: ischemic hypoxic; labor; hypoxic stress; non laboring ... See more keywords
Time series assessment of the effects of hypoxic stress on glioma tumorsphere development within engineered microscale niches.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.12.018
Abstract: A rapidly outgrowing tumor mass is liable to suffer from a shortage of oxygen and nutrients due to the diffusion limit. These features evidently prevail in glioblastoma, resulting in extensive hypoxic regions throughout the tumor… read more here.
Keywords: time series; time; hypoxic stress; stress ... See more keywords
SMARCB1 regulates the hypoxic stress response in sickle cell trait
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2209639120
Abstract: Significance SMARCB1 is a tumor suppressor that is universally inactivated in renal medullary carcinoma (RMC), a highly aggressive malignancy that predominantly afflicts young individuals of African descent with sickle cell trait (SCT). We demonstrated using… read more here.
Keywords: cell; sickle cell; cell trait; hypoxic stress ... See more keywords
Hypoxic stress visualized in the cervical spinal cord of ALS patients
Sign Up to like & getrecommendations! Published in 2020 at "Neurological Research"
DOI: 10.1080/01616412.2020.1866383
Abstract: ABSTRACT Objective: Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron disease. Hypoxic stress is suspected as the pathogenesis of ALS, however, no positron emission tomography (PET) study for hypoxic stress has been… read more here.
Keywords: als patients; cord als; spinal cord; hypoxic stress ... See more keywords
A combined computational pipeline to detect circular RNAs in human cancer cells under hypoxic stress
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjz094
Abstract: Abstract Hypoxia is associated with several diseases, including cancer. Cells that are deprived of adequate oxygen supply trigger transcriptional and post-transcriptional responses, which control cellular pathways such as angiogenesis, proliferation, and metabolic adaptation. Circular RNAs… read more here.
Keywords: circular rnas; human cancer; computational pipeline; hypoxic stress ... See more keywords
Transcriptomic responses of the liver of mandarin fish (Siniperca chuatsi) under hypoxic stress.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of fish biology"
DOI: 10.1111/jfb.15399
Abstract: Environmental hypoxia is becoming more prevalent in aquatic environments of mandarin fish (Siniperca chuatsi) aquaculture because of eutrophication and climate change. Little information is available on the molecular mechanisms of the detrimental effects of hypoxia… read more here.
Keywords: stress; siniperca chuatsi; fish siniperca; hypoxic stress ... See more keywords
The Damage Mechanisms of Dark Hypoxic Stress on Photosystem II of Cymodocea rotundata
Sign Up to like & getrecommendations! Published in 2022 at "Photochemistry and Photobiology"
DOI: 10.1111/php.13641
Abstract: Hypoxic stress is a major threat to the survival of seagrass but its damage mechanism is unclear. In order to explore the causes of seagrass meadow decline due to hypoxia, the effects of hypoxia in… read more here.
Keywords: stress; damage; hypoxic stress; dark hypoxic ... See more keywords
Yap-Hippo Signaling Activates Mitochondrial Protection and Sustains Breast Cancer Viability under Hypoxic Stress
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Oncology"
DOI: 10.1155/2021/5212721
Abstract: Yes-associated protein (Yap) is a transcriptional regulator that upregulates oncogenes and downregulates tumor repressor genes. In this study, we analyzed protein expression, RNA transcription, and signaling pathways to determine the function and mechanism of Yap… read more here.
Keywords: hypoxic stress; breast cancer; stress; yap ... See more keywords
Neuroglobin Is Involved in the Hypoxic Stress Response in the Brain
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/8263373
Abstract: Neuroglobin is an oxygen-binding heme protein expressed predominantly in the brain. Despite many years of research, the exact distribution and expression of neuroglobin in the neocortical development and under mild hypoxia stress still remain unclear.… read more here.
Keywords: stress; expression neuroglobin; brain; hypoxic stress ... See more keywords
Hypoxic stress disrupts HGF/Met signaling in human trophoblasts: implications for the pathogenesis of preeclampsia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-022-00791-5
Abstract: Background Preeclampsia (PE), a placenta-associated pregnancy complication, is the leading cause of maternal and perinatal morbidity and mortality. Met/Erk signaling is inhibited in the placentas of patients with early-onset preeclampsia (E-PE), but the underlying mechanisms… read more here.
Keywords: hgf met; endocytosis; met signaling; pathogenesis preeclampsia ... See more keywords
Insights into soybean transcriptome reconfiguration under hypoxic stress: Functional, regulatory, structural, and compositional characterization
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0187920
Abstract: Soybean (Glycine max) is one of the major crops worldwide and flooding stress affects the production and expansion of cultivated areas. Oxygen is essential for mitochondrial aerobic respiration to supply the energy demand of plant… read more here.
Keywords: soybean transcriptome; insights soybean; hypoxic stress; stress ... See more keywords