MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming
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DOI: 10.15252/embr.202255643
Abstract: Extensive desmoplasia and poor vasculature renders pancreatic tumors severely hypoxic, contributing to their aggressiveness and therapy resistance. Here, we identify the HuR/MYB/HIF1α axis as a critical regulator of the metabolic plasticity and hypoxic survival of… read more here.
Keywords: pancreatic cancer; hypoxic survival; myb; survival pancreatic ... See more keywords