Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model
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DOI: 10.1371/journal.ppat.1009527
Abstract: Baloxavir is approved in several countries for the treatment of uncomplicated influenza in otherwise-healthy and high-risk patients. Treatment-emergent viruses with reduced susceptibility to baloxavir have been detected in clinical trials, but the likelihood of widespread… read more here.
Keywords: susceptibility; host fitness; ferret model; fitness ... See more keywords