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   Articles with "i3c" as a keyword



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Attenuating effect of Indole-3-Carbinol on gold nanoparticle induced hepatotoxicity in rats

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recommendations! Published in 2020 at "Arabian Journal of Chemistry"

DOI: 10.1016/j.arabjc.2020.09.035

Abstract: Abstract Indole-3-carbinol (I3C) is a plant based compound present in vegetables mostly belonging to cruciferous family. I3C has been shown to possess anticancer, antioxidant and anti-inflammatory properties. Humans are increasingly being exposed to GNPs due… read more here.

Keywords: i3c; indole carbinol; gnps; effects i3c ... See more keywords
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The International Childhood Cardiovascular Cohort (i3C) consortium outcomes study of childhood cardiovascular risk factors and adult cardiovascular morbidity and mortality: Design and recruitment.

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recommendations! Published in 2018 at "Contemporary clinical trials"

DOI: 10.1016/j.cct.2018.04.009

Abstract: Although it is widely thought that childhood levels of cardiovascular (CV) risk factors are related to adult CV disease, longitudinal data directly linking the two are lacking. This paper describes the design and organization of… read more here.

Keywords: childhood; i3c; risk factors; cohort ... See more keywords
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Enhanced nuclear translocation and activation of aryl hydrocarbon receptor (AhR) in THP-1 monocytic cell line by a novel niosomal formulation of indole-3-carbinol

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recommendations! Published in 2019 at "Journal of Liposome Research"

DOI: 10.1080/08982104.2019.1600545

Abstract: Abstract Although niosomes structurally resemble liposomes, they are composed of nonionic surfactants which result in less toxicity and more stability. Here, we developed a novel niosomal formulation of I3C and investigated the nuclear translocation and… read more here.

Keywords: niosomal formulation; i3c; nuclear translocation; thp ... See more keywords

Glucobrassicin Metabolites Ameliorate the Development of Portal Hypertension and Cirrhosis in Bile Duct-Ligated Rats

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recommendations! Published in 2019 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms20174161

Abstract: Patients suffering from liver cirrhosis are often complicated with the formation of portosystemic collateral vessels, which is associated with the progression of a splanchnic hyperdynamic circulatory state. Alleviating pathological angiogenesis has thus been proposed to… read more here.

Keywords: angiogenesis; cirrhosis; i3c; bile duct ... See more keywords
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Indole-3-Carbinol Inhibits the Growth of Endometriotic Lesions by Suppression of Microvascular Network Formation

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recommendations! Published in 2022 at "Nutrients"

DOI: 10.3390/nu14224940

Abstract: Endometriosis represents an estrogen-dependent disorder with a complex pathophysiology. Phytochemicals are promising candidates for endometriosis therapy, because they simultaneously target different cellular processes involved in the pathogenesis of endometriosis. Herein, we analyzed whether indole-3-carbinol (I3C)… read more here.

Keywords: growth; endometriotic lesions; formation; i3c ... See more keywords