Tryptophan Metabolic Enzyme IL4I1 Inhibits Ferroptosis by Decreasing Ubiquitination of Nrf2 via I3P in Glioblastoma
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DOI: 10.1111/cpr.13816
Abstract: Glioblastoma multiforme (GBM) is the deadliest brain tumour with an extremely poor prognosis. Tryptophan catabolism could enhance an array of protumour‐genic signals and promoted tumour progression in GBM. However, the mechanisms of oncogenic signalling under… read more here.
Keywords: metabolic enzyme; i3p; tryptophan metabolic; gbm ... See more keywords