Three Novel Mutations I65S, R66S, and G86R Divulge Significant Conformational Variations in the PTB Domain of the IRS1 Gene
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DOI: 10.1021/acsomega.8b01712
Abstract: Insulin receptor substrate 1 (IRS1) is one of the major substrates for the IR, and their interaction mediates several downstream insulin signaling pathways. In this study, we have identified three novel mutations in the IRS1… read more here.
Keywords: i65s r66s; novel mutations; three novel; irs1 ... See more keywords