The IAP family member BRUCE regulates autophagosome–lysosome fusion
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-02823-x
Abstract: Autophagy has an important role in cellular homeostasis by degrading and recycling cytotoxic components. Ubiquitination is known to target cargoes for autophagy; however, key components of this pathway remain elusive. Here we performed an RNAi… read more here.
Keywords: lysosome fusion; iap family; bruce; fusion ... See more keywords
A Pan-Cancer Analysis of the BIRC Gene Family and Its Association with Prognosis, Tumor Microenvironment, and Therapeutic Targets.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2021038714
Abstract: The inhibitors of apoptosis protein (IAP)/baculoviral IAP repeat containing (BIRC) gene families are necessary for cell protection, and most of these genes act as endogenous inhibitors of apoptosis. In some cancers, the over-expression of the… read more here.
Keywords: iap family; prognosis; cancer; gene ... See more keywords