Immunotherapy with nebulized pattern recognition receptor agonists restores severe immune paralysis and improves outcomes in mice with influenza-associated pulmonary aspergillosis
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DOI: 10.1128/mbio.04061-24
Abstract: ABSTRACT Influenza-associated pulmonary aspergillosis (IAPA) is a potentially deadly superinfection in patients with influenza pneumonia, especially those with severe disease, underlying immunosuppression, corticosteroid therapy, or requiring intensive care support. Given the high mortality of IAPA,… read more here.
Keywords: receptor; therapy; influenza; mortality ... See more keywords
Detecting influenza-associated pulmonary aspergillosis by determination of galactomannan in broncho-alveolar lavage fluid and in serum: should we add (1,3)-beta-D-glucan to improve efficacy
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DOI: 10.1186/s13054-020-03030-1
Abstract: We read with great interest the recent research letter by Thevissen et al. who reported the findings of their international survey regarding the detection of influenzaassociated pulmonary aspergillosis (IAPA), with a focus on the use… read more here.
Keywords: aspergillosis; pulmonary aspergillosis; iapa; alveolar lavage ... See more keywords
Clinical features of influenza-associated pulmonary aspergillosis: a retrospective multicenter cohort study
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DOI: 10.3389/fcimb.2025.1648547
Abstract: Rationale Influenza-associated pulmonary aspergillosis (IAPA) is a great clinical challenge, which has high morbidity and mortality in severe influenza infections. Unlike invasive pulmonary aspergillosis (IPA), IAPA often occurs in immunocompetent hosts. That IAPA lacks of… read more here.
Keywords: microbiology; rate; study; iapa ... See more keywords
Managing the Next Wave of Influenza and/or SARS-CoV-2 in the ICU—Practical Recommendations from an Expert Group for CAPA/IAPA Patients
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DOI: 10.3390/jof9030312
Abstract: The aim of this study was to establish practical recommendations for the diagnosis and treatment of influenza-associated invasive aspergillosis (IAPA) based on the available evidence and experience acquired in the management of patients with COVID-19-associated… read more here.
Keywords: iapa; practical recommendations; capa iapa; management ... See more keywords