Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes.
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DOI: 10.1172/jci.insight.151349
Abstract: Human islet antigen reactive CD4+ memory T cells (IAR T cells) play a key role in the pathogenesis of autoimmune type 1 diabetes (T1D). Using single-cell RNA sequencing (scRNA-Seq) to identify T cell receptors (TCRs)… read more here.
Keywords: iar cells; tcr junctions; type diabetes; tcrs ... See more keywords