Improved detection of influenza A virus from blue‐winged teals by sequencing directly from swab material
Sign Up to like & getrecommendations! Published in 2019 at "Ecology and Evolution"
DOI: 10.1002/ece3.5232
Abstract: Abstract The greatest diversity of influenza A virus (IAV) is found in wild aquatic birds of the orders Anseriformes and Charadriiformes. In these birds, IAV replication occurs mostly in the intestinal tract. Fecal, cloacal, and/or… read more here.
Keywords: detection; diversity; iav; virus isolation ... See more keywords
Inhibition effects of novel polyketide compound PPQ‐B against influenza A virus replication by interfering with the cellular EGFR pathway
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.04.007
Abstract: Abstract Development of anti‐influenza A virus (IAV) drugs with novel targets and low toxicity is critical for preparedness against influenza outbreaks. In the current study, our results indicated that the novel polyketide compound purpurquinone B… read more here.
Keywords: iav; inhibition; ppq; virus replication ... See more keywords
Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-02035-9
Abstract: The risk of emerging pandemic influenza A viruses (IAVs) that approach the devastating 1918 strain motivates finding strain-specific host–pathogen mechanisms. During infection, dendritic cells (DC) mature into antigen-presenting cells that activate T cells, linking innate… read more here.
Keywords: influenza viruses; iav; cell; cell death ... See more keywords
The Streptococcus pyogenes fibronectin/tenascin-binding protein PrtF.2 contributes to virulence in an influenza superinfection
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29714-x
Abstract: Influenza A virus (IAV) and Streptococcus pyogenes (the group A Streptococcus; GAS) are important contributors to viral-bacterial superinfections, which result from incompletely defined mechanisms. We identified changes in gene expression following IAV infection of A549… read more here.
Keywords: streptococcus pyogenes; iav; prtf; gas ... See more keywords
Influenza A virus diffusion through mucus gel networks.
Sign Up to like & getrecommendations! Published in 2022 at "Communications biology"
DOI: 10.1038/s42003-022-03204-3
Abstract: Mucus in the lung plays an essential role as a barrier to infection by viral pathogens such as influenza A virus (IAV). Previous work determined mucin-associated sialic acid acts as a decoy receptor for IAV… read more here.
Keywords: mucus gel; mucus; diffusion; influenza virus ... See more keywords
Inhibition of Influenza A Virus Infection by Fucoidan Targeting Viral Neuraminidase and Cellular EGFR Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40760
Abstract: Development of novel anti-influenza A virus (IAV) drugs with high efficiency and low toxicity is critical for preparedness against influenza outbreaks. Herein, we investigated the anti-IAV activities and mechanisms of fucoidan in vitro and in… read more here.
Keywords: viral neuraminidase; egfr; iav; infection ... See more keywords
Influenza A virus exploits transferrin receptor recycling to enter host cells
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2214936120
Abstract: Significance We still have an incomplete understanding of the proteins influenza A virus (IAV) uses to enter the host cell. Here we demonstrate that IAV entry is diminished in the absence of transferrin receptor 1… read more here.
Keywords: iav; transferrin receptor; host; enter host ... See more keywords
Antibody Immunodominance: The Key to Understanding Influenza Virus Antigenic Drift.
Sign Up to like & getrecommendations! Published in 2018 at "Viral immunology"
DOI: 10.1089/vim.2017.0129
Abstract: Influenza A virus (IAV) imposes a significant socioeconomic burden on humanity. Vaccination is effective in only 60% of individuals, even under optimal circumstances. The difficulty stems from the remarkable ability of IAV to evade existing… read more here.
Keywords: influenza virus; antibody immunodominance; influenza; iav ... See more keywords
Basic fibroblast growth factor protects against influenza A virus-induced acute lung injury by recruiting neutrophils
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjx047
Abstract: Influenza virus (IAV) infection is a major cause of severe respiratory illness that affects almost every country in the world. IAV infections result in respiratory illness and even acute lung injury and death, but the… read more here.
Keywords: acute lung; influenza virus; lung injury; iav ... See more keywords
Attenuation of interferon regulatory factor 7 activity in local infectious sites of trachea and lung for preventing the development of acute lung injury caused by influenza A virus
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1111/imm.13045
Abstract: The excessive activation of interferon regulatory factor 7 (IRF7) promotes the development of acute lung injury (ALI) caused by influenza A virus (IAV). However, the deficiency of IRF7 increases the susceptibility to deadly IAV infection… read more here.
Keywords: iav; local infectious; activity local; activity ... See more keywords
Serological and molecular epidemiological study on swine influenza in Zambia.
Sign Up to like & getrecommendations! Published in 2021 at "Transboundary and emerging diseases"
DOI: 10.1111/tbed.14373
Abstract: Influenza A viruses (IAVs) cause highly contagious respiratory diseases in humans and animals. In 2009, a swine-origin pandemic H1N1 IAV, designated A(H1N1)pdm09 virus, spread worldwide, and has since frequently been introduced into pig populations. Since… read more here.
Keywords: iav; zambia; h1n1 pdm09; influenza ... See more keywords