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   Articles with "iav" as a keyword



Improved detection of influenza A virus from blue‐winged teals by sequencing directly from swab material

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recommendations! Published in 2019 at "Ecology and Evolution"

DOI: 10.1002/ece3.5232

Abstract: Abstract The greatest diversity of influenza A virus (IAV) is found in wild aquatic birds of the orders Anseriformes and Charadriiformes. In these birds, IAV replication occurs mostly in the intestinal tract. Fecal, cloacal, and/or… read more here.

Keywords: detection; diversity; iav; virus isolation ... See more keywords

Inhibition effects of novel polyketide compound PPQ‐B against influenza A virus replication by interfering with the cellular EGFR pathway

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recommendations! Published in 2017 at "Antiviral Research"

DOI: 10.1016/j.antiviral.2017.04.007

Abstract: Abstract Development of anti‐influenza A virus (IAV) drugs with novel targets and low toxicity is critical for preparedness against influenza outbreaks. In the current study, our results indicated that the novel polyketide compound purpurquinone B… read more here.

Keywords: iav; inhibition; ppq; virus replication ... See more keywords

Quantitatively Dissecting Triple Roles of Dynactin in Dynein-Driven Transport of Influenza Virus by Quantum Dot-Based Single-Virus Tracking.

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recommendations! Published in 2024 at "ACS nano"

DOI: 10.1021/acsnano.4c10564

Abstract: After entering host cells by endocytosis, influenza A virus (IAV) is transported along microfilaments and then transported by dynein along microtubules (MTs) to the perinuclear region for genome release. Understanding the mechanisms of dynein-driven transport… read more here.

Keywords: transport; virus; driven transport; iav ... See more keywords

Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death

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recommendations! Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-02035-9

Abstract: The risk of emerging pandemic influenza A viruses (IAVs) that approach the devastating 1918 strain motivates finding strain-specific host–pathogen mechanisms. During infection, dendritic cells (DC) mature into antigen-presenting cells that activate T cells, linking innate… read more here.

Keywords: influenza viruses; iav; cell; cell death ... See more keywords

Prior infection with unrelated neurotropic virus exacerbates influenza disease and impairs lung T cell responses

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recommendations! Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-46822-7

Abstract: Immunity to infectious diseases is predominantly studied by measuring immune responses towards a single pathogen, although co-infections are common. In-depth mechanisms on how co-infections impact anti-viral immunity are lacking, but are highly relevant to treatment… read more here.

Keywords: lung; cd8; pathology; virus ... See more keywords

The Streptococcus pyogenes fibronectin/tenascin-binding protein PrtF.2 contributes to virulence in an influenza superinfection

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-29714-x

Abstract: Influenza A virus (IAV) and Streptococcus pyogenes (the group A Streptococcus; GAS) are important contributors to viral-bacterial superinfections, which result from incompletely defined mechanisms. We identified changes in gene expression following IAV infection of A549… read more here.

Keywords: streptococcus pyogenes; iav; prtf; gas ... See more keywords

Influenza A virus diffusion through mucus gel networks.

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recommendations! Published in 2022 at "Communications biology"

DOI: 10.1038/s42003-022-03204-3

Abstract: Mucus in the lung plays an essential role as a barrier to infection by viral pathogens such as influenza A virus (IAV). Previous work determined mucin-associated sialic acid acts as a decoy receptor for IAV… read more here.

Keywords: mucus gel; mucus; diffusion; influenza virus ... See more keywords

Inhibition of Influenza A Virus Infection by Fucoidan Targeting Viral Neuraminidase and Cellular EGFR Pathway

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep40760

Abstract: Development of novel anti-influenza A virus (IAV) drugs with high efficiency and low toxicity is critical for preparedness against influenza outbreaks. Herein, we investigated the anti-IAV activities and mechanisms of fucoidan in vitro and in… read more here.

Keywords: viral neuraminidase; egfr; iav; infection ... See more keywords

Influenza A virus exploits transferrin receptor recycling to enter host cells

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recommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2214936120

Abstract: Significance We still have an incomplete understanding of the proteins influenza A virus (IAV) uses to enter the host cell. Here we demonstrate that IAV entry is diminished in the absence of transferrin receptor 1… read more here.

Keywords: iav; transferrin receptor; host; enter host ... See more keywords

Antibody Immunodominance: The Key to Understanding Influenza Virus Antigenic Drift.

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recommendations! Published in 2018 at "Viral immunology"

DOI: 10.1089/vim.2017.0129

Abstract: Influenza A virus (IAV) imposes a significant socioeconomic burden on humanity. Vaccination is effective in only 60% of individuals, even under optimal circumstances. The difficulty stems from the remarkable ability of IAV to evade existing… read more here.

Keywords: influenza virus; antibody immunodominance; influenza; iav ... See more keywords

Basic fibroblast growth factor protects against influenza A virus-induced acute lung injury by recruiting neutrophils

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recommendations! Published in 2018 at "Journal of Molecular Cell Biology"

DOI: 10.1093/jmcb/mjx047

Abstract: Influenza virus (IAV) infection is a major cause of severe respiratory illness that affects almost every country in the world. IAV infections result in respiratory illness and even acute lung injury and death, but the… read more here.

Keywords: acute lung; influenza virus; lung injury; iav ... See more keywords