Modeling an immune response to influenza A virus infection in alveolar epithelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28284
Abstract: Influenza A viruses (IAV) have been the cause of several influenza pandemics in history and are a significant threat for the next global pandemic. Hospitalized influenza patients often have excess interferon production and a dysregulated… read more here.
Keywords: infection; influenza; immune response; alveolar epithelial ... See more keywords
Protective effects of SP600125 on mice infected with H1N1 influenza A virus
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Virology"
DOI: 10.1007/s00705-021-05103-0
Abstract: Influenza A virus (IAV) can cause high morbidity and mortality globally every year. Myriad host kinases and their related signaling pathways are involved in IAV infection, and the important role of the c-Jun N-terminal kinase… read more here.
Keywords: h1n1; influenza virus; iav infection; virus ... See more keywords
TGF-β1 signaling inhibit the in vitro apoptotic, infection and stimulatory cell response induced by influenza H1N1 virus infection on A549 cells.
Sign Up to like & getrecommendations! Published in 2021 at "Virus research"
DOI: 10.1016/j.virusres.2021.198337
Abstract: Influenza A virus (IAV) infection induces host cell responses that could derive in inflammatory and apoptotic response. In this respect, in multiple pathological situations, TGF-β1 has shown anti-inflammatory effect, but its role during IAV infection… read more here.
Keywords: tgf signaling; response; infection; cell ... See more keywords
Phosphorylation of JIP4 at S730 Presents Antiviral Properties against Influenza A Virus Infection
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virology"
DOI: 10.1128/jvi.00672-21
Abstract: Influenza A virus (IAV) infection is a world health concern, and current treatment options encounter high rates of resistance. Our group investigates host pathways modified in IAV infection as promising new targets. ABSTRACT Influenza A… read more here.
Keywords: iav infection; jip4; infection; phosphorylation ... See more keywords
Influenza A Virus Uses PSMA2 for Downregulation of the NRF2-Mediated Oxidative Stress Response
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01990-21
Abstract: Influenza A virus (IAV) remains one of the most significant infectious agents, responsible for 3 million to 5 million illnesses each year and more than 50 million deaths during the 20th century. The cellular processes… read more here.
Keywords: psma2; iav infection; influenza virus; nrf2 mediated ... See more keywords
Acute Influenza Infection Promotes Lung Tumor Growth by Reprogramming the Tumor Microenvironment.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-22-0534
Abstract: One billion people worldwide get flu every year, including patients with non-small cell lung cancer (NSCLC). However, the impact of acute influenza A virus (IAV) infection on the composition of the tumor microenvironment (TME) and… read more here.
Keywords: infection; tumor microenvironment; lung tumor; acute influenza ... See more keywords
Tollip Inhibits IL-33 Release and Inflammation in Influenza A Virus-Infected Mouse Airways.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of innate immunity"
DOI: 10.1159/000525315
Abstract: Respiratory influenza A virus (IAV) infection continues to pose significant challenges in healthcare of human diseases including asthma. IAV infection in mice was shown to increase IL-33, a key cytokine in driving airway inflammation in… read more here.
Keywords: inflammation; release; iav infection; influenza virus ... See more keywords
Enzymatic independent role of sphingosine kinase 2 in regulating the expression of type I interferon during influenza A virus infection
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010794
Abstract: Influenza virus has the ability to circumvent host innate immune system through regulating certain host factors for its effective propagation. However, the detailed mechanism is still not fully understood. Here, we report that a host… read more here.
Keywords: enzymatic independent; infection; ifn; iav infection ... See more keywords
Influenza a virus and Streptococcus pneumonia coinfection potentially promotes bacterial colonization and enhances B lymphocyte depression and reduction.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/19-240-a
Abstract: Influenza has frequently been epidemic in recent years. However, the mechanisms of severe pneumonia with postinfluenza Streptococcus pneumoniae (SP) secondary infection have not been fully understood. In this study, we explored the mechanisms of pneumonia… read more here.
Keywords: iav infection; infection alone; infection; colonization ... See more keywords
Enhancing the natural killer cell activity and anti-influenza effect of heat-treated Lactobacillus plantarum nF1-fortified yogurt in mice.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of dairy science"
DOI: 10.3168/jds.2018-15137
Abstract: Influenza A virus (IAV) infection is a global public health concern. It causes respiratory diseases ranging from mild illness to fatal disease. Natural killer (NK) cells are an innate immune component that kill infected cells… read more here.
Keywords: fortified yogurt; plantarum nf1; iav infection; nf1 fortified ... See more keywords
Influenza Virus Infection Induces ZBP1 Expression and Necroptosis in Mouse Lungs
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00286
Abstract: Programmed cell death and especially necroptosis, a programmed and regulated form of necrosis, have been recently implicated in the progression and outcomes of influenza in mouse models. Moreover, Z-DNA/RNA binding protein 1 (ZBP1) has been… read more here.
Keywords: mouse lungs; infection; necroptosis; iav infection ... See more keywords