Analytical validation of the IBD segment-based tool KinSNP® for human identification applications.
Sign Up to like & getrecommendations! Published in 2025 at "BioTechniques"
DOI: 10.1080/07366205.2025.2454770
Abstract: KinSNP® v1.0, a software tool for human identification, has been widely used to measure IBD segment sharing between individuals using dense SNP data. Herein, the tool was validated using simulated pedigree data (up to 9th… read more here.
Keywords: ibd segment; human identification; kinsnp; tool ... See more keywords
Open-source benchmarking of IBD segment detection methods for biobank-scale cohorts
Sign Up to like & getrecommendations! Published in 2022 at "GigaScience"
DOI: 10.1093/gigascience/giac111
Abstract: Abstract In the recent biobank era of genetics, the problem of identical-by-descent (IBD) segment detection received renewed interest, as IBD segments in large cohorts offer unprecedented opportunities in the study of population and genealogical history,… read more here.
Keywords: detection methods; open source; ibd segment; segment detection ... See more keywords
Evaluating the Impact of Dropout and Genotyping Error on SNP-Based Kinship Analysis With Forensic Samples
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.882268
Abstract: Technological advances in sequencing and single nucleotide polymorphism (SNP) genotyping microarray technology have facilitated advances in forensic analysis beyond short tandem repeat (STR) profiling, enabling the identification of unknown DNA samples and distant relationships. Forensic… read more here.
Keywords: genotyping error; forensic samples; error; snp ... See more keywords
Evaluation of Four Forensic Investigative Genetic Genealogy Analysis Approaches with Decreased Numbers of SNPs and Increased Genotyping Errors
Sign Up to like & getrecommendations! Published in 2024 at "Genes"
DOI: 10.3390/genes15101329
Abstract: Background: Forensic investigative genetic genealogy (FIGG) has developed rapidly in recent years and is considered a novel tool for crime investigation. However, crime scene samples are often of low quality and quantity and are challenging… read more here.
Keywords: ibd segment; mom; segment based; genotyping errors ... See more keywords