Robust Wet Milling Technique for Producing Micronized Ibuprofen Particles with Improved Solubility and Dissolution
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DOI: 10.1208/s12249-022-02480-w
Abstract: This study investigated a systematic approach for producing ibuprofen (IBF) particles with leucine by wet milling. Using a high shear homogenizer, the particles size of the IBF was reduced. Prepared IBF microparticles were freeze-dried and… read more here.
Keywords: solubility dissolution; solubility; wet milling; ibf ... See more keywords