Enhancement of the oral bioavailability of isopropoxy benzene guanidine though complexation with hydroxypropyl-β-cyclodextrin
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DOI: 10.1080/10717544.2022.2118400
Abstract: Abstract Isopropoxy benzene guanidine (IBG) is a novel substituted benzene guanidine analogue with antibacterial activity against multidrug-resistant bacteria. However, the bioavailability of IBG is not optimal due to its finite aqueous solubility, thus hampering its… read more here.
Keywords: isopropoxy benzene; guanidine; bioavailability; benzene guanidine ... See more keywords